BiologicalActivity
Orallyactiveproteaseinhibitor.Knowntoinhibittrypsinandvariousinflammatoryproteasesincludingplasmin,kallikreinandthrombin.Suppressespancreatitis-inducedpaininratsfollowingoraladmiNISTration.
CompoundLibraries
CamostatmesylateisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 494.52 |
| Formula | C20H22N4O5.CH3SO3H |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| CASNumber | 59721-29-8 |
| PubChemID | 43071 |
| InChIKey | FSEKIHNIDBATFG-UHFFFAOYSA-N |
| Smiles | O=C(C2=CC=C(NC(N)=N)C=C2)OC1=CC=C(CC(OCC(N(C)C)=O)=O)C=C1.CS(=O)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.45 | 100 | |
| water | 49.45 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight494.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.02mL | 10.11mL | 20.22mL |
| 5mM | 0.4mL | 2.02mL | 4.04mL |
| 10mM | 0.2mL | 1.01mL | 2.02mL |
| 50mM | 0.04mL | 0.2mL | 0.4mL |
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