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Description:γ-secretaseinhibitor
AlternativeNames:CW
ChemicalName:3,5-Bis(4-nitrophenoxy)benzoicacid
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Inhibitorofγ-secretase;causesadecreaseinthereleasedlevelsofAβ42andnotch-1Aβ-likepeptide25(Nβ25).
TechnicalData
M.Wt | 396.31 |
Formula | C19H12N2O8 |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 173550-33-9 |
PubChemID | 16760376 |
InChIKey | JOSXKPZXMVHRKU-UHFFFAOYSA-N |
Smiles | OC(=O)C1=CC(OC2=CC=C(C=C2)[N+]([O-])=O)=CC(OC2=CC=C(C=C2)[N+]([O-])=O)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
1.1eq.NaOH | 19.81 | 50 | |
DMSO | 39.63 | 100 | |
ethanol | 1.98 | 5 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight396.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.52mL | 12.62mL | 25.23mL |
5mM | 0.5mL | 2.52mL | 5.05mL |
10mM | 0.25mL | 1.26mL | 2.52mL |
50mM | 0.05mL | 0.25mL | 0.5mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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