Tocris产品促销 TOCRIS 4372-10MG,Tocris/Z-DEVD-FMK/2166/1/1 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Z-DEVD-FMK/2166/1/1 mg

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Tocris

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2166/1

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4000-520-616

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Description:Cell-permeable,irreversIBLecaspase-3inhibitor

ChemicalName:Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeable,irreversibleinhibitorofcaspase-3/CPP32;inhibitstumorcellapoptosis.Neuroprotectiveinrathippocampusfollowingseizuresinvivo.

TechnicalData

M.Wt	668.67
Formula	C₃₀H₄₁FN₄O₁₂
Sequence	DEVD (Modifications:Asp-1=Z-Asp(OMe),Glu-2=Glu(OMe),Asp-4=(OMe)-fluoromethylketone)
Storage	Storeat-20°C
PubChemID	16760394
InChIKey	GBJVAVGBSGRRKN-JYEBCORGSA-N
Smiles	[H]N([C@@H](CC(=O)OC)C(=O)N[C@@H](CCC(=O)OC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)C(=O)OCC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto13.37mg/mlinDMSO

Solubility

Solubleto13.37mg/mlinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight668.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.5mL	7.48mL	14.96mL
5mM	0.3mL	1.5mL	2.99mL
10mM	0.15mL	0.75mL	1.5mL
50mM	0.03mL	0.15mL	0.3mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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SolubilityData

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