BiologicalActivity
Immunosuppressiveagent;blocksphagocytosis,cytokineproductionandproliferationofTandBcells.Non-competitivelyinhibitschymotrypsin-likeactivityof20Sproteasome;preventsdegradationofIκBα,anendogenousblockerofNF-κB.AlsoinhibitsfarnesyltransferaseandgeranylgeranyltransferaseI(IC50valuesare80and17μMrespectively)anddisplaysantitumoractivityagainstbreastcancerinvivo.
TechnicalData
| M.Wt | 326.38 |
| Formula | C13H14N2O4S2 |
| Storage | Desiccateat-20°C |
| CASNumber | 67-99-2 |
| PubChemID | 6223 |
| InChIKey | FIVPIPIDMRVLAY-RBJBARPLSA-N |
| Smiles | O=C([C@@]2(SS4)N(C([C@@]43CO)=O)[C@@H]1[C@@H](O)C=CC=C1C2)N3C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | SolubleinDMSOandinethanol |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight326.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.06mL | 15.32mL | 30.64mL |
| 5mM | 0.61mL | 3.06mL | 6.13mL |
| 10mM | 0.31mL | 1.53mL | 3.06mL |
| 50mM | 0.06mL | 0.31mL | 0.61mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。