中国Tocris公司正品Tocris Bioscience生物试剂1,Tocris/K 579/2790/10/10 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/K 579/2790/10/10 mg

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Tocris

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2790/10

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4000-520-616

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Description:DipeptidylpeptidaseIV(DPP-IV)inhibitor

ChemicalName:(2S)-1-[[[4-Methyl-1-(2-pyrimidinyl)-4-piperidinyl]amino]acetyl]-2-pyrrolidinecarbonitrile

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

DipeptidylpeptidaseIVinhibitor.Inhibitsrat,canine,humanandmonkeyenzymeswithIC₅₀valuesof3,5,8,and8nMrespectively.Long-actinghypoglycemicagent;attenuatesglucoseexcursionfollowingglucoseloADInginZuckerfattyrats.

TechnicalData

M.Wt	328.41
Formula	C₁₇H₂₄N₆O
Storage	Desiccateat+4°C
Purity	≥99%(HPLC)
CASNumber	440100-64-1
PubChemID	9818824
InChIKey	JERPHRNGJBSFAP-AWEZNQCLSA-N
Smiles	O=C(CNC2(C)CCN(C3=NC=CC=N3)CC2)N1CCC[C@H]1C#N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	1eq.HCl	16.42	50
	DMSO	32.84	100
	ethanol	6.57	20

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight328.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.04mL	15.22mL	30.45mL
5mM	0.61mL	3.04mL	6.09mL
10mM	0.3mL	1.52mL	3.04mL
50mM	0.06mL	0.3mL	0.61mL

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