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Description:Inositolmonophosphataseinhibitor
ChemicalName:[1-(4-Hydroxyphenoxy)ethylidene]bisphosphonicacid
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Apotentinhibitorofinositolmonophophatase;stabletohydrolysis.InducesautophagyinCOS-7cellsindependentlyofmTORinhibition.
LicensingInformation
SoldwiththepermissionofMerckSharpandDohmeLtd.
TechnicalData
M.Wt | 298.13 |
Formula | C8H12O8P2 |
Storage | StoreatRT |
CASNumber | 142523-38-4 |
PubChemID | 132449 |
InChIKey | JKOCAAWWDVHWKB-UHFFFAOYSA-N |
Smiles | CC(OC1=CC=C(O)C=C1)(P(O)(O)=O)P(O)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
phosphatebufferedsaline | 29.81 | 100mMwithgentlewarming | |
DMSO | 29.81 | 100mMwithgentlewarming | |
ethanol | 14.91 | 50mMwithgentlewarming | |
water | 29.81 | 100mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight298.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.35mL | 16.77mL | 33.54mL |
5mM | 0.67mL | 3.35mL | 6.71mL |
10mM | 0.34mL | 1.68mL | 3.35mL |
50mM | 0.07mL | 0.34mL | 0.67mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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