BiologicalActivity
Apotentinhibitorofinositolmonophophatase;stabletohydrolysis.InducesautophagyinCOS-7cellsindependentlyofmTORinhibition.
LicensingInformation
SoldwiththepermissionofMerckSharpandDohmeLtd.
TechnicalData
| M.Wt | 298.13 |
| Formula | C8H12O8P2 |
| Storage | StoreatRT |
| CASNumber | 142523-38-4 |
| PubChemID | 132449 |
| InChIKey | JKOCAAWWDVHWKB-UHFFFAOYSA-N |
| Smiles | CC(OC1=CC=C(O)C=C1)(P(O)(O)=O)P(O)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| phosphatebufferedsaline | 29.81 | 100mMwithgentlewarming | |
| DMSO | 29.81 | 100mMwithgentlewarming | |
| ethanol | 14.91 | 50mMwithgentlewarming | |
| water | 29.81 | 100mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight298.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.35mL | 16.77mL | 33.54mL |
| 5mM | 0.67mL | 3.35mL | 6.71mL |
| 10mM | 0.34mL | 1.68mL | 3.35mL |
| 50mM | 0.07mL | 0.34mL | 0.67mL |
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