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Description:Fluorogeniccaspasesubstrate
ChemicalName:N-Acetyl-Leu-Glu-His-Asp-(7-amino-4-trifluoromethylcoumarin)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Fluorogeniccaspasesubstrate.Analogofthecaspase-9substrate,LEHD-AFC.
TechnicalData
| M.Wt | 765.7 |
| Formula | C33H38F3N7O11 |
| Sequence | LEHD (Modifications:Leu-1=N-Ac-Leu,Asp-4=Asp-(7-amino-4-trifluoromethylcoumarin)) |
| Storage | Desiccateat-20°C |
| CASNumber | 210345-03-2 |
| PubChemID | 25108576 |
| InChIKey | HULKIXRFKRCRHD-ZJZGAYNASA-N |
| Smiles | CC(C)C[C@H](NC(C)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CC(O)=O)C(=O)NC1=CC=C2C(OC(=O)C=C2C(F)(F)F)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight765.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.31mL | 6.53mL | 13.06mL |
| 5mM | 0.26mL | 1.31mL | 2.61mL |
| 10mM | 0.13mL | 0.65mL | 1.31mL |
| 50mM | 0.03mL | 0.13mL | 0.26mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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