Tocris经销商/代理商 Tocris Bioscience中国采购,Tocris/Marimastat/2631/1/1 mg,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Marimastat/2631/1/1 mg

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Tocris

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2631/1

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4000-520-616

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Description:BroadspectrumMMPinhibitor

AlternativeNames:BB2516,Marimistat

ChemicalName:(2S,3R)-N4-[(1S)-2,2-Dimethyl-1-[(methylamino)carbonyl]propyl]-N1,2-dihydroxy-3-(2-methylpropyl)butanediamide

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

BroadspectruminhibitorofMMPs(IC₅₀valuesare3,5,6,9and13nMforMMP-9,MMP-1,MMP-2,MMP-14andMMP-7respectively).Inhibitsperitonealdisseminationofhumangastriccancercellsinvivothroughinhibitionoftumorangiogenesis.

TechnicalData

M.Wt	331.41
Formula	C₁₅H₂₉N₃O₅
Storage	Storeat-20°C
Purity	≥99%(HPLC)
CASNumber	154039-60-8
PubChemID	119031
InChIKey	OCSMOTCMPXTDND-OUAUKWLOSA-N
Smiles	O=C(NO)[C@@H](O)[C@H]([C@](N[C@@H]([C@](C)(C)C)C(NC)=O)=O)CC(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	33.14	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight331.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.02mL	15.09mL	30.17mL
5mM	0.6mL	3.02mL	6.03mL
10mM	0.3mL	1.51mL	3.02mL
50mM	0.06mL	0.3mL	0.6mL

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BiologicalActivity

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