Tocris产品目录价格 Tocris Bioscience授权代理商，正品,Tocris/Okadaic acid/1136/25U/25 ug,蛋白酶类,酶,蛋白类,,Tocris Bioscience蚂蚁淘商城

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Tocris/Okadaic acid/1136/25U/25 ug

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Tocris

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1136/25U

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4000-520-616

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Description:Proteinphosphatase1and2Ainhibitor

ChemicalName:9,10-Deepithio-9,10-didehydroacanthifolicin

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinhibitorofproteinphosphatase1(IC₅₀=3nM)andproteinphosphatase2A(IC₅₀=0.2-1nM).Displays>100,000,000-foldselectivityoverPP2BandPP2C.Tumorpromoter.ShowntoactivateatypicalproteinkinaseCinADIpocytes.

TechnicalData

M.Wt	805.01
Formula	C₄₄H₆₈O₁₃
Storage	Desiccateat-20°C
CASNumber	78111-17-8
PubChemID	90479758
InChIKey	QNDVLZJODHBUFM-QRJUTTKYSA-N
Smiles	[H][C@@](CCCO5)([H])[C@](CC[C@H]4C)5O[C@@H]4[C@@H](C)C[C@H](O)C(C([C@H]3O)=C)OC(C3O2)CC[C@]12O[C@@H](/C=C/[C@H]([C@H](O7)CC(C)=C[C@@]67[C@H](O)CCC(C[C@](O)(C)C(O)=O)O6)C)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	80.5	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight805.01.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.24mL	6.21mL	12.42mL
5mM	0.25mL	1.24mL	2.48mL
10mM	0.12mL	0.62mL	1.24mL
50mM	0.02mL	0.12mL	0.25mL

ProductDatasheets

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BiologicalActivity

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