BiologicalActivity
Caspase-3activator.ActsviainhibitionoftheoncoproteinProT,thereforestimulatesapoptosomeformationandsubsequentcaspase-3activationinacytochromec-dependentmanner.
TechnicalData
| M.Wt | 240.52 |
| Formula | C8H8Cl3NO |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 10129-56-3 |
| PubChemID | 224859 |
| InChIKey | NGTDJJKTGRNNAU-UHFFFAOYSA-N |
| Smiles | OC(CC1=CC=NC=C1)C(Cl)(Cl)Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| 1eq.HCl | 12.03 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight240.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.16mL | 20.79mL | 41.58mL |
| 5mM | 0.83mL | 4.16mL | 8.32mL |
| 10mM | 0.42mL | 2.08mL | 4.16mL |
| 50mM | 0.08mL | 0.42mL | 0.83mL |
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