BiologicalActivity
Non-selectiveproteaseinhibitor;irreversIBLysulfonateskeyactivesiteserineresiduesinserineproteases,acetylcholinesterases,andthiolproteases.Blocksmetabolismofanandamide(Cat.No.1339)inarodentmodelofcannABImimeticactivity.Unstableinwater(t1/2~60minsatpH7.5).Brainpenetrant.
TechnicalData
| M.Wt | 174.19 |
| Formula | C7H7FO2S |
| Storage | DesiccateatRT |
| Purity | ≥98% |
| CASNumber | 329-98-6 |
| PubChemID | 4784 |
| InChIKey | YBYRMVIVWMBXKQ-UHFFFAOYSA-N |
| Smiles | O=S(CC1=CC=CC=C1)(F)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 17.42 | 100 | |
| ethanol | 17.42 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight174.19.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 5.74mL | 28.7mL | 57.41mL |
| 5mM | 1.15mL | 5.74mL | 11.48mL |
| 10mM | 0.57mL | 2.87mL | 5.74mL |
| 50mM | 0.11mL | 0.57mL | 1.15mL |
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