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Tocris/Perindopril erbumine/4302/50/50 mg

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Tocris/Perindopril erbumine/4302/50/50 mg

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Tocris

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4302/50

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4000-520-616

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Description:Angiotensin-convertingenzyme(ACE)inhibitor

ChemicalName:(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylicacidtert-butylaminesalt

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Angiotensin-convertingenzyme(ACE)inhibitor(IC₅₀=1.05nM).Brainpenetrant.SuppressestheincreaseinhippocampalACEactivityandimprovescognitioninPS2APP-transgenicmice.

TechnicalData

M.Wt	441.6
Formula	C₁₉H₃₂N₂O₅.C₄H₁₁N
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	107133-36-8
PubChemID	441313
InChIKey	IYNMDWMQHSMDDE-MHXJNQAMSA-N
Smiles	C[C@H](N[C@H]([C@@](OCC)=O)CCC)C(N1[C@H]([C@@](O)=O)C[C@@]2([H])[C@@]([H])1CCCC2)=O.NC(C)(C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	2.21	5
	ethanol	22.08	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight441.6.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.26mL	11.32mL	22.64mL
5mM	0.45mL	2.26mL	4.53mL
10mM	0.23mL	1.13mL	2.26mL
50mM	0.05mL	0.23mL	0.45mL

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