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Tocris/Phosphoramidon disodium salt/6333/5/5 mg
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Tocris/Phosphoramidon disodium salt/6333/5/5 mg
品牌 / 
Tocris
货号 / 
6333/5
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Description:Neutralendopeptidaseandendothelinconvertingenzymeinhibitor
ChemicalName:N-[N-[[(6-Deoxy-α-L-mannopyranosyl)oxy]hydroxyphosphinyl]-L-leucyl]-L-tryptophandisodiumsalt
Purity:≥95%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Neutralendopeptidase(neprilysin)inhibitor.BlocksdegradationofamyloidβpeptidesandincreasesAβlevelsinrodents.Alsoblocksendothelinconvertingenzyme(ECE).

TechnicalData

M.Wt587.47
FormulaC23H32N3Na2O10P
StorageStoreat-20°C
Purity≥95%(HPLC)
CASNumber164204-38-0
PubChemID16219931
InChIKeyOQKHVXFOYFBMDJ-ODIUWQMJSA-L
SmilesCC(C[C@@H](C(N[C@H](C(O[Na])=O)CC1=CNC2=CC=CC=C12)=O)NP(O[C@@H]3O[C@H]([C@@H]([C@H]([C@H]3O)O)O)C)(O[Na])=O)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water58.75100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight587.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.7mL8.51mL17.02mL
5mM0.34mL1.7mL3.4mL
10mM0.17mL0.85mL1.7mL
50mM0.03mL0.17mL0.34mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet