Tocris试剂采购 Tocris Bioscience美元价/进货价,Tocris/Ritonavir/5856/50/50 mg,蛋白酶类,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Ritonavir/5856/50/50 mg

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Tocris

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5856/50

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Description:HIV-1andHIV-2proteaseinhibitor

AlternativeNames:ABT-538,A-84538,Abbot84538

ChemicalName:5-Thiazolylmethyl(3S,4S,6S,9S)-4-hydroxy-12-methyl-9-(1-methylethyl)-13-[2-(1-methylethyl)-4-thiazolyl]-8,11-dioxo-3,6-bis(phenylmethyl)-2,7,10,12-tetraazatridecanoate

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HIV-1andHIV-2proteaseinhibitor(EC₅₀valuesare0.022-0.13and0.16μM,respectively).BlocksthemetabolismofproteaseinhibitorsbyliverenzymecytochromeP450-3A4(CYP3A4).Orallybioavailable.

TechnicalData

M.Wt	720.94
Formula	C₃₇H₄₈N₆O₅S₂
Storage	Storeat-20°C
Purity	≥98%(HPLC)
CASNumber	155213-67-5
PubChemID	392622
InChIKey	NCDNCNXCDXHOMX-XGKFQTDJSA-N
Smiles	O[C@@H](C[C@@H](NC([C@H](C(C)C)NC(N(C)CC1=CSC(C(C)C)=N1)=O)=O)CC2=CC=CC=C2)[C@@H](NC(OCC3=CN=CS3)=O)CC4=CC=CC=C4

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	14.42	20mMwithgentlewarming
	ethanol	7.21	10

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight720.94.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.39mL	6.94mL	13.87mL
5mM	0.28mL	1.39mL	2.77mL
10mM	0.14mL	0.69mL	1.39mL
50mM	0.03mL	0.14mL	0.28mL

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