生命科学Tocris价格优惠 Tocris Bioscience试剂产品信息,Tocris/Ro 32-3555/2916/10/10 mg,蛋白酶类,Tocris,Bio-Techne,,10 mg蚂蚁淘商城

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Tocris/Ro 32-3555/2916/10/10 mg

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Tocris

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2916/10

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4000-520-616

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Description:Potent,Collagenase-selectiveMMPinhibitor

ChemicalName:(αR,βR)-β-(Cyclopentylmethyl)-N-hydroxy-γ-oxo-α-[(3,4,4-trimethyl-2,5-dioxo-1-imidazolidinyl)methyl]-1-piperidiNEButanamide

Purity:≥97%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potent,collagenase-selectiveMMPinhibitor(K_ivaluesare3.0,3.4,4.4,59,154and527nMforMMP-1,MMP-13,MMP-8,MMP-9,MMP-2andMMP-3respectively).Inhibitscartilagebreakdowninvitroandinvivoanddisplaysantiarthriticactivity.Orallyactive.

TechnicalData

M.Wt	436.55
Formula	C₂₂H₃₆N₄O₅
Storage	Storeat-20°C
Purity	≥97%(HPLC)
CASNumber	190648-49-8
PubChemID	9824350
InChIKey	GFUITADOEPNRML-SJORKVTESA-N
Smiles	O=[C@@](N3CCCCC3)[C@H](CC1CCCC1)[C@@H]([C@](NO)=O)CN2C(N(C)C(C)(C)C2=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	43.66	100
	ethanol	43.66	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight436.55.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.29mL	11.45mL	22.91mL
5mM	0.46mL	2.29mL	4.58mL
10mM	0.23mL	1.15mL	2.29mL
50mM	0.05mL	0.23mL	0.46mL

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