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Description:Potentfurininhibitor
ChemicalName:rel-N,N''-[[(1R,3S,4S,6R)-4,6-Bis[(aminoiminomethyl)amino]-1,3-cyclohexanedyil]bis(oxy-4,1-phenylene)]bisguanidinetetratrifluoroacetatesalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentfurininhibitor(EC50=54nM).Blocksfurin-dependentcellsurfaceprocessingofanthraxprotectiveantigen-83invitro.
TechnicalData
| M.Wt | 952.66 |
| Formula | C22H32N12O2.4CF3CO2H |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 922732-52-3 |
| PubChemID | 121513857 |
| InChIKey | JYRRXGHBFAELIV-YAOLEPIASA-N |
| Smiles | NC(N[C@H]1C[C@@H](NC(N)=N)[C@H](OC3=CC=C(NC(N)=N)C=C3)C[C@@H]1OC2=CC=C(NC(N)=N)C=C2)=N.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O.FC(F)(F)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.66 | 100 | |
| water | 49.66 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight952.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.05mL | 5.25mL | 10.5mL |
| 5mM | 0.21mL | 1.05mL | 2.1mL |
| 10mM | 0.1mL | 0.52mL | 1.05mL |
| 50mM | 0.02mL | 0.1mL | 0.21mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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