商品信息
联系客服

郑重提醒:
无质量问题不接受退换货,下单前请仔细核对信息。
下单后请及时联系客服核对商品价格,订单生效后再付款。
Description:SelectiveinhibitorofeIF2αdephosphorylation
ChemicalName:3-Phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Cell-permeable,selectiveinhibitorofcellularphosphatasecomplexesthatdephosphorylateeukaryotictranslationinitiationfactor2subunitα(eIF2α).Protectscellsfromendoplasmicreticulumstress-inducedapoptosis(EC50~15μM).
CompoundLibraries
SalubrinalisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 479.81 |
Formula | C21H17N4OSCl3 |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 405060-95-9 |
PubChemID | 5717801 |
InChIKey | LCOIAYJMPKXARU-VAWYXSNFSA-N |
Smiles | S=C(NC(NC(/C=C/C3=CC=CC=C3)=O)C(Cl)(Cl)Cl)NC1=C2C(C=CC=N2)=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 47.98 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight479.81.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.08mL | 10.42mL | 20.84mL |
5mM | 0.42mL | 2.08mL | 4.17mL |
10mM | 0.21mL | 1.04mL | 2.08mL |
50mM | 0.04mL | 0.21mL | 0.42mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


▍
品牌分类
▍
官网分类
▍
品牌问答