Tocris试剂采购 Tocris Bioscience一级代理,Tocris/Saquinavir mesylate/4418/10/10 mg,蛋白酶类,Tocris,Bio-Techne,,10 mg蚂蚁淘商城

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Tocris/Saquinavir mesylate/4418/10/10 mg

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Tocris/Saquinavir mesylate/4418/10/10 mg

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Tocris

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4418/10

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4000-520-616

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Description:HIVproteaseinhibitor

AlternativeNames:Ro31-8959

ChemicalName:(2S)-N1-[(1S,2R)-3-[(3S,4aS,8aS)-3-[[(1,1-dimethylethyl)amino]carbonyl]octahydro-2(1H)-isoquinolinyl]-2-hydroxy-1-(phenylmethyl)propyl]-2-[(2-quinolinylcarbonyl)amino]butanediamidemethanesulfonate

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofhumanimmunodeficiencyvirus(HIV)protease(K_ivaluesare<0.1and0.12nMforHIV-2andHIV-1proteaserespectively).Exhibitshighantiviralactivityandlowcytotoxicity.

CompoundLibraries

SaquinavirmesylateisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	766.95
Formula	C₃₈H₅₀N₆O₅.CH₄O₃S
Storage	Storeat+4°C
Purity	≥99%(HPLC)
CASNumber	149845-06-7
PubChemID	60934
InChIKey	IRHXGOXEBNJUSN-YOXDLBRISA-N
Smiles	O=C(N[C@@H](CC(N)=O)C(N[C@@H](CC4=CC=CC=C4)[C@H](O)CN3C[C@](CCCC5)([H])[C@]5([H])C[C@H]3[C@@](NC(C)(C)C)=O)=O)C2=NC1=CC=CC=C1C=C2.CS(=O)(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	38.35	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight766.95.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.3mL	6.52mL	13.04mL
5mM	0.26mL	1.3mL	2.61mL
10mM	0.13mL	0.65mL	1.3mL
50mM	0.03mL	0.13mL	0.26mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

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