Tocris厂家直采，平行进口 Tocris Bioscience产品目录价格,Tocris/Z-VAD-FMK/2163/1/1 mg,蛋白酶类,Tocris,Bio-Techne,,1 mg蚂蚁淘商城

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Tocris/Z-VAD-FMK/2163/1/1 mg

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Tocris

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2163/1

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4000-520-616

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Description:Cell-permeable,irreversIBLecaspaseinhibitor

ChemicalName:Benzyloxycarbonyl-Val-Ala-Asp(OMe)-fluoromethylketone

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Cell-permeable,irreversiblepan-caspaseinhibitor.Inhibitscaspaseprocessingandapoptosisinductionintumorcellsinvitro(IC₅₀=0.0015-5.8mM).Activeinvivo.

TechnicalData

M.Wt	467.49
Formula	C₂₂H₃₀FN₃O₇
Sequence	VAD (Modifications:Val-1=Z-Val,Asp-3=(OMe)-fluoromethylketone)
Storage	Storeat-20°C
CASNumber	187389-52-2
PubChemID	5497174
InChIKey	MIFGOLAMNLSLGH-QOKNQOGYSA-N
Smiles	[H]N([C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(=O)OC)C(=O)CF)C(=O)OCC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

Solubility	Solubleto9.35mg/mlinDMSO

Solubility

Solubleto9.35mg/mlinDMSO

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight467.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.14mL	10.7mL	21.39mL
5mM	0.43mL	2.14mL	4.28mL
10mM	0.21mL	1.07mL	2.14mL
50mM	0.04mL	0.21mL	0.43mL

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SolubilityData

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