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Description:PotentandselectiveinhibitorofMMP-13
ChemicalName:N-[2-[4-[[[2-[(Hydroxyamino)carbonyl]-4,6-dimethylphenyl](phenylmethyl)amino]sulfonyl]phenoxy]ethyl]-2-benzofurancarboxamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
PotentandselectiveinhibitorofMMP-13(IC50valuesare17,945,>1000and>10000nMforMMP-13,MMP-9,TACEandMMP-1respectively).
CompoundLibraries
WAY170523isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 613.68 |
| Formula | C33H31N3O7S |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 307002-73-9 |
| PubChemID | 9830392 |
| InChIKey | FARMEEAGJWMFSZ-UHFFFAOYSA-N |
| Smiles | CC1=CC(C(=O)NO)=C(N(CC2=CC=CC=C2)S(=O)(=O)C2=CC=C(OCCNC(=O)C3=CC4=CC=CC=C4O3)C=C2)C(C)=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 61.37 | 100 | |
| ethanol | 61.37 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight613.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.63mL | 8.15mL | 16.3mL |
| 5mM | 0.33mL | 1.63mL | 3.26mL |
| 10mM | 0.16mL | 0.81mL | 1.63mL |
| 50mM | 0.03mL | 0.16mL | 0.33mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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