BiologicalActivity
Inhibitorofprolylendopeptidase,aserinepeptidasethatmaybeimplicatedinthebiosynthesisofamyloidβ-peptide.Potentlyinhibitsratbrainprolylendopeptidase(Ki=0.95nM)invitro,andpreventsamyloidβ-peptidedepositioninvivo.Orallyactiveandbrainpenetrant.
TechnicalData
| M.Wt | 508.69 |
| Formula | C23H34N2OS2.C2H2O4 |
| Storage | Storeat-20°C |
| Purity | ≥96%(HPLC) |
| CASNumber | 146794-84-5 |
| PubChemID | 45073463 |
| InChIKey | UUSSHPPSOUAHHP-UHFFFAOYSA-N |
| Smiles | O=C(C2=CC=CS2)C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C.O=C(C(=O)O)O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 7.63 | 15 | |
| ethanol | 7.63 | 15mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight508.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.97mL | 9.83mL | 19.66mL |
| 5mM | 0.39mL | 1.97mL | 3.93mL |
| 10mM | 0.2mL | 0.98mL | 1.97mL |
| 50mM | 0.04mL | 0.2mL | 0.39mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。