进口Tocris品牌清关代理 Tocris Bioscience产品目录价格,Tocris/Y-29794 oxalate/1634/50/50 mg,蛋白酶类,Tocris,Bio-Techne,,50 mg蚂蚁淘商城

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Tocris/Y-29794 oxalate/1634/50/50 mg

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Tocris

货号 /

1634/50

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4000-520-616

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Description:Prolylendopeptidaseinhibitor

ChemicalName:[2-[[8-(Dimethylamino)octyl]thio]-6-(1-methylethyl)-3-pyridinyl]-2-thienylmethanoneoxalate

Purity:≥96%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inhibitorofprolylendopeptidase,aserinepeptidasethatmaybeimplicatedinthebiosynthesisofamyloidβ-peptide.Potentlyinhibitsratbrainprolylendopeptidase(K_i=0.95nM)invitro,andpreventsamyloidβ-peptidedepositioninvivo.Orallyactiveandbrainpenetrant.

TechnicalData

M.Wt	508.69
Formula	C₂₃H₃₄N₂OS₂.C₂H₂O₄
Storage	Storeat-20°C
Purity	≥96%(HPLC)
CASNumber	146794-84-5
PubChemID	45073463
InChIKey	UUSSHPPSOUAHHP-UHFFFAOYSA-N
Smiles	O=C(C2=CC=CS2)C1=CC=C(C(C)C)N=C1SCCCCCCCCN(C)C.O=C(C(=O)O)O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	7.63	15
	ethanol	7.63	15mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight508.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.97mL	9.83mL	19.66mL
5mM	0.39mL	1.97mL	3.93mL
10mM	0.2mL	0.98mL	1.97mL
50mM	0.04mL	0.2mL	0.39mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

TechnicalData

SolubilityData

PreparingStockSolutions

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