BiologicalActivity
Broadspectrum,irreversibleinhibitorofserineproteases.AlsoinhibitsNADPHoxidaseactivationinvitro.Attenuatesairwayinflammationinamousemodelofairwayallergy.
TechnicalData
| M.Wt | 239.69 |
| Formula | C8H10FNO2S.HCl |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 30827-99-7 |
| PubChemID | 186136 |
| InChIKey | WRDABNWSWOHGMS-UHFFFAOYSA-N |
| Smiles | NCCC1=CC=C(S(=O)(F)=O)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 23.97 | 100 | |
| water | 23.97 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight239.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.17mL | 20.86mL | 41.72mL |
| 5mM | 0.83mL | 4.17mL | 8.34mL |
| 10mM | 0.42mL | 2.09mL | 4.17mL |
| 50mM | 0.08mL | 0.42mL | 0.83mL |
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