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Assaypro/Corticosterone AssayMax ELISA Kit/96 Well Plate/EC3001-1
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Assaypro/Corticosterone AssayMax ELISA Kit/96 Well Plate/EC3001-1
品牌 / 
Assaypro
货号 / 
EC3001-1
美元价:
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数    量:
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4000-520-616
DETAILS
Description:This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Type:AssayMax ELISA Kits
Samples:

Serum

Plasma

Cell Culture

Urine

Saliva

Milk

Catalog Number:EC3001-1
Species:None
Format:Competitive ELISA
Size:96 Well Plate
Range:0.391 - 100 ng/ml
Research Area:Adrenal, Cardiac Disorder
Synonyms:corticosterone, cort, cortico
Note:For Research Use Only, Not To Be Used For Diagnostic Purposes
Product References:
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(2008) Activation of Trk neurotrophin receptors by glucocorticoids provides a neuroprotective effect.Proc. Natl. Acad. Sci. U.S.A. 105:4862-4867 *Kevill KA et al. (2008) A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome.The Journal of Immunology 180(1): 601-608 *Umekawa T et al. (2008) Overexpression of Thioredoxin-1 Reduces Oxidative Stress in the Placenta of Transgenic Mice and Promotes Fetal Growth via Glucose Metabolism.Endocrinology 149(8):3980-3988*Satvat E (2009) Neural and Behavioural Effects of the Ginkgo biloba Leaf Extract Egb 761. Theses and Dissertations (Comprehensive). Paper 1070*Beaulieu M et al. (2010) Ecophysiological response of Adelie penguins facing an experimental increase in breeding constraints. J. Experimental Biology 213:33-39 *Beaulieu M et al. (2010) When sea-ice clock is ahead of Adelie penguins? clock.Functional Ecology 24:93-102*Chai W (2010) Steroidogenesis vs. steroid uptake in the heart: do corticosteroids mediate effects via cardiac mineralocorticoid receptors? J. Hypertension 28:1044-1053 *Gamliel-Lazarovich A et al. (2010) Paraoxonase 1 deficiency in mice is associated with reduced steroid biosynthesis: Effects on HDL binding, cholesteryl ester accumulation and scavenger receptor type BI expression. Atherosclerosis 211:130-135*Hayasaka D et al. (2010) Early Mortality Following Intracerebral Infection with the Oshima Strain of Tick-Borne Encephalitis Virus in a Mouse Model. J. Vet. Med. Sci. 72(4): 391-396*Huang HJ et al. (2010) The interaction between acute oligomer Abeta(1-40) and stress severely impaired spatial learning and memory. Neurobiol Learn Mem. 93(1):8-18 *Izbeki F et al. (2010) Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice. J. Physiology 588(16):3101-17*Qiao J et al. (2010) Identification of steroid biosynthetic defects in genotype-proven heterozygous individuals for 17alpha-hydroxylase/17,20-lyase deficiency. Clin Endocrinol (Oxf). 72(3):312-319*Schulz K and Korz V (2010) Emotional and cognitive information processing: Relations to behavioral performance and hippocampal long-term potentiation in vivo during a spatial water maze training in rats. Learning Memory 17:552-560 *Schulz K and Korz V (2010) Hippocampal testosterone relates to reference memory performance and synaptic plasticity in male rats. Front Behav Neurosci. 4:187 *Spee M et al. (2010) Should I stay or should I go? Hormonal control of nest abandonment in a long-lived bird, the Adelie penguin. Horm. Behav. 58(5):762-8 * Toriya M et al. (2010) Long-term Infusion of Brain-Derived Neurotrophic Factor Reduces Food Intake and Body Weight via a Corticotrophin-Releasing Hormone Pathway in the Paraventricular Nucleus of the Hypothalamus. J. 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(2011) Resveratrol prevents the wasting disorders of mechanical unloading by acting as a physical exercise mimetic in the rat. FASEB J. 25(10):3646-3660* Murakami T et al. (2011) Rapid induction of REDD1 expression by endurance exercise in rat skeletal muscle. Biochem Biophys Res Commun. 405(4):615-619.*Nakamura Y et al. (2011) Circadian clock gene Period2 regulated a time-of-day-dependent variation in curaneous anaphylactic reaction. J Allergy Clin Immunol. 127(4):1038-45.e1-3*Oh YT et al. (2011) Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue. Am J Physiol Endocrinol Metab 300(6): E1012-E1021*Schroeder M et al. (2011) Enriched Environment Moderates Obesity in Genetically Hyperphagic OLETF Rats in a Sex-dependent Manner. ILAR e-Journal. 52:e39-e45 *Spee M et al. (2011) Exogenous corticosterone and nest abandonment: A study in a long-lived bird, the Adelie penguin. Horm Behav. 60(4):362-70. Epub 2011 Jul 13 *Spee M et al. (2011) Exogenous corticosterone mimics a late fasting stage in captive Adelie penguins (Pygoscelis adeliae). Am J Physiol Regul Integr Comp Physiol 300: R1241-R1249*Tang JI (2011) Prenatal Glucocorticoid Programming of 11-beta Hydoxysteroid Dehydrogenase Type 2 and Erythropoietin in the Kieney. The University of Edinburgy.*Tang JI et al. (2011) Prenatal Glucocorticoid Overexposure Causes Permanent Increases in Renal Erythropoietin Expression and Red Blood Cell Mass in the Rat Offspring. Endocrinology. 152(7):2716-2721*Tanaka M et al. (2011) Role of Central Leptin Signaling in the Starvation-Induced Alteration of B-Cell Development. J Neurosci. 31(23):8373-8380*Terada Y et al. (2011) Dietary Vitamin E Deficiency Increases Anxiety-Like Behavior in Juvenile and Adult Rats. Biosci Biotechnol Biochem. 2011;75(10):1894-9. Epub 2011 Oct 7* Wang Z et al (2011) Preventive Action of Panax ginseng Roots in Hypercortisolism-induced Impairment of Hippocampal Neurons in Male C57BL/6N Mice. Phytother Res. 25(8):1242-1245.*Williams CL et al. (2011) Mouse maternal systemic inflammation at the zygote stage causes blunted cytokine responsiveness in lipopolysaccharide-challenged adult offspring. BMC Biol. 9:49* Young TO at al. (2011) Continuous 24-h nicotinic acid infusion in rats causes FFA rebound and insulin resistance by altering gene expression and basal lipolysis in adipose tissue. Am J Physiol Endocrinol Metab. 300(6): E1012?E1021*Edelstein S et al. (2012) Salvia sclarea seed oil for use in the treatment of cardiovascular diseases or anxiety disorders. Patent Application number: WO2012156970 A1*Fukada M et al. (2012 ) Loss of Deacetylation Activity of Hdac6 Affects Emotional Behavior in Mice. PLoS One. 7(2):e30924 *Jeanneteau FD et al. (2012) BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus. Proc Natl Acad Sci U S A. 109(4):1305-1310* Ikeda Y et al. (2012) Heat shock protein expression inducer. Patent application: WO2012043808 A1, PCT / JP2011 / 072592 * Kondo S et al. (2015) Antidepressant-like effects of rosmarinic acid through mitogen-activated protein kinase phosphatase-1 and brain-derived neurotrophic factor modulation. Journal of Functional Foods. 14:758-766* Kogure M et al. (2012) Moxibustion at Mingmen Reduces Inflammation and Decreases IL-6 in a Collagen-Induced Arthritis Mouse Model. J Acupunct Meridian Stud. 5(1):29-33*LeGates TA et al. (2012) Aberrant light directly impairs mood and learning through melanopsin-expressing neurons. Nature. 491(7425):594-598*Mahmoud UT et al. (2012) The Effect of Separate-Sex Rearing of Slaughter Quail on Serum Corticosterone Level. Journal of Advanced Veterinary Research 2:206-207 *Moussaieff A et al. (2012) Incensole acetate reduces depressive-like behavior and modulates hippocampal BDNF and CRF expression of submissive animals. J Psychopharmacol 26(12):1584-1593*Sherman H et al. (2012) Timed high-fat diet resets circadian metabolism and prevents obesity. FASEB J. 26(8):3493-3502* Sujino M et al. (2012) Differential Entrainment of Peripheral Clocks in the Rat by Glucocorticoid and Feeding. Endocrinology 153(5):2277-2286* Yamada H et al. (2012) Methionine excess in diet induces acute lethal hepatitis in mice lacking cystathionine gamma-lyase, an animal model of cystathioninuria. Free Radic Biol Med. 52(9):1716-1726*Yanai S (2012) Remarkable Changes in Behavior and Physiology of Laboratory Mice after the Massive 2011 Tohoku Earthquake in Japan. PLoS One. 7(9):e44475 *Yoshioka M et al. (2012) Effects of Parabolic Flight on Serotonin-Related Gene Expression in the Mouse Brain. Gravitational and Space Biology 26 (2):22-29*Chapnik N et al. (2013) A superactive leptin antagonist alters metabolism and locomotion in high leptin mice. J Endocrinol. 217(3):283-90 *Hayasaka D et al. (2013) TNF-alpha Acts as an Immunoregulator in the Mouse Brain by Reducing the Incidence of Severe Disease Following Japanese Encephalitis Virus Infection. PLoS ONE. 8(8):e71643*Sakai H et al. (2013) Effects of radiofrequency Radiation at 40 kHz on stress-induced immune response in mice. J.Rakuno Gakuen Univ. 37(2):189-194*Liston C et al. (2013) Circadian glucocorticoid oscillations promote learning-dependent synapse formation and maintenance. Nature Neuroscience 16:698-705 *McGuire JL et al.(2013) Traits of fear resistance and susceptibility in an advanced intercross line. Eur J Neurosci. 38(9):3314-24. doi: 10.1111/ejn.12337. Epub 2013 Aug 22*Miyazaki K et al. (2013) Continuous exposure to a novel stressor based on water aversion induces abnormal circadian locomotor rhythms and sleep-wake cycles in mice. PLoS One. 8(1):e55452. Epub 2013 Jan 30*Oishi K and Ohkura N (2013) Chronic circadian clock disruption induces expression of the cardiovascular risk factor plasminogen activator inhibitor-1 in mice. Blood Coagul Fibrinolysis. 24(1):106-8*Othman MB et al. (2013) Antistress Effects of the Ethanolic Extract from Cymbopogon schoenanthus Growing Wild in Tunisia.Evidence-Based Complementary and Alternative Medicine.Volume 2013 (2013), Article ID 737401, 9 pages* Oue H et al. (2013) Tooth loss induces memory impairment and neuronal cell loss in APP transgenic mice. Behav Brain Res. 252:318-325* Shinohara H et al. (2013) Medium-chain fatty acid-containing dietary oil alleviates the depression-like behaviour in mice exposed to stress due to chronic forced swimming. Journal of Funtional Foods. 5(2):601-606*Spinelli S et al. (2013) Effects of repeated adolescent stress and serotonin transporter gene partial knockout in mice on behaviors and brain structures relevant to major depression. Front Behav Neurosci. 2013 Dec 31;7:215* Tabassum H et al. (2013) The effect of acute swim stress and training in the water maze on hippocampal synaptic activity as well as plasticity in the dentate gyrus of freely moving rats: Revisiting swim?induced LTP reinforcement. Hippocampus. 23(12):1291-8*Thierry AM et al. (2013) Decreased prolactin levels reduce parental commitment, egg temperatures, and breeding success of incubating male Adelie penguins. Hormones and Behavior 64 (4):737-747 *Torres OV et al. (2013) Behavioral, Biochemical, and Molecular Indices of Stress are Enhanced in Female Versus Male Rats Experiencing Nicotine Withdrawal. Front Psychiatry. 2013 May 20;4:38* Wilson CL et al. (2013) Chemotherapy drug thioTEPA exacerbates stress-induced anhedonia and corticosteroid responses but not impairment of hippocampal cell proliferation in adult mice. Behav Brain Res. 236(1):180-185*Abe K et al. (2014) Withdrawal of repeated morphine enhances histamine-induced scratching responses in mice. Drug Chem Toxicol. 4:1-7*Bentley L et al. (2014) An N-Ethyl-N-Nitrosourea Induced Corticotropin-Releasing Hormone Promoter Mutation Provides a Mouse Model for Endogenous Glucocorticoid Excess.Endocrinology. 155(3):908-22.Epub 2013 Dec 3. *Cottin M et al. (2014) Corticosterone administration leads to a transient alteration of foraging behaviour and complexity in a diving seabird. Marine Ecology Progress Series 496:249-262 * Cottin M et al. (2014) Decreasing prolactin levels leads to a lower diving effort but does not affect breeding success in Ad?lie penguins. Hormones and Behavior. 65(2):134-141.*Hiramoto K et al. (2014) Relationship between alteration of the peptide hormone levels and depression during the gestational period. Res.J.Endocrinol. Metab. 2:1. * Jung SM et ahcl. (2014) Cytokine-Mediated Bone Destruction in Rheumatoid Arthritis. J Immunol Res. 2014:263625*Kuhn E et al. (2014) Paradoxical resistance to high-fat diet-induced obesity and altered macrophage polarization in mineralocorticoid receptor-overexpressing mice. Am J Physiol Endocrinol Metab. 306(1):E75-90. doi: 10.1152/ajpendo.00323.2013. Epub 2013 Nov 12.* Mizuki D et al. (2014) Antidepressant-like effect of Butea superba in mice exposed to chronic mild stress and its possible mechanism of action. J Ethnopharmacol. 156:16-25* Nakamura Y et al. (2014) Circadian regulation of allergic reactions by the mast cell clock in mice. J. Allergy Clin. Immunol. 133 (2):568-575* Nahata M et al. (2014) Administration of exogenous acylated ghrelin or rikkunshito, an endogenous ghrelin enhancer, improves the decrease in postprandial gastric motility in an acute restraint stress mouse model. Neurogastroenterol Motil. 26:821-831*Takemoto H et al. (2014) Inhalation administration of valerena-4,7(11)-diene from Nardostachys chinensis roots ameliorates restraint stress-induced changes in murine behavior and stress-related factors. Biol Pharm Bull. 37(6):1050-5* Tamura Y et al. (2014) Postexercise whole body heat stress additively enhances endurance training-induced mitochondrial adaptations in mouse skeletal muscle.Am J Physiol Regul Integr Comp Physiol. 307(7):R931-43*Guillou A et al. (2015) Assessment of Lactotroph Axis Functionality in Mice: Longitudinal Monitoring of PRL Secretion by Ultrasensitive-ELISA. Endocrinology. 156(5):1924-1930*Hori A et al. (2015) Kososan, but not milnacipran, elicits antidepressant-like effects in a novel psychological stress-induced mouse model of depression. Traditional & Kampo Medicine 2(1):1-7*Iwasaki S et al. (2015) Brief fear preexposure facilitates subsequent fear conditioning. Neurosci Res. 95:66-73* Nagahama K et al. (2015) Effect of kumquat (Fortunella crassifolia) pericarp on natural killer cell activity in vitro and in vivo. Biosci Biotechnol Biochem. 79(8):1327-36.* Nakao R et al. (2015) Atypical expression of circadian clock genes in denervated mouse skeletal muscle. Chronobiol Int. 2015 May;32(4):486-96. doi:10.3109/07420528.2014.1003350. Epub 2015 Mar 23* Oishi K et al. (2015) Disrupted light?dark cycle abolishes circadian expression of peripheral clock genes without inducing behavioral arrhythmicity in mice. Biochem Biophys Res Commun. 458(2):256-261* Shimizu S (2015) Yokukansan normalizes glucocorticoid receptor protein expression in oligodendrocytes of the corpus callosum by regulating microRNA-124a expression after stress exposure. Brain Res Bull. 114:49-55* Zhang H et al. (2015) Chronic corticosterone exposure reduces hippocampal astrocyte structural plasticity and induces hippocampal atrophy in mice. Neurosci Lett. 592:76-81* Yasumoto Y et al. (2015) Free Access to a Running-Wheel Advances the Phase of Behavioral and Physiological Circadian Rhythms and Peripheral Molecular Clocks in Mice. PLoS One. 2015; 10(1): e0116476* Antunes MS et al. (2015) Neuropeptide Y administration reverses tricyclic antidepressant treatment-resistant depression induced by ACTH in mice. Horm Behav. 73:56-63* Bath KG et al. (2016) Early life stress accelerates behavioral and neural maturation of the hippocampus in male mice. Horm Behav. 82:64-71 * Bertile F (2016) The Safety Limits Of An Extended Fast: Lessons from a Non-Model Organism. Sci Rep. 2016 Dec 19;6:39008* Lesburgueres et al.(2016) Active place avoidance is no more stressful than unreinforced exploration of a familiar environment. Hippocampus. 26(12):1481-1485.* Mukuta K et al. (2016) Administration of Tomato Juice or Aqueous Components of Tomato Reduces Fatigue Induced by Acute Treadmill Exercise. Food and Nutritiion Sciences. 7(7):524-532.* Nakamura Y et al. (2016) Effects of inducing exercise on growing mice by means of three-dimensional structure in rearing environment. Exp Anim. 65(4): 403-411* Ono M. et al. (2016) Does the routine handling affect the phenotype of disease model mice? Japanese Journal of Veterinary Research 64(4): 265-271* Uwaya A et al. (2016) Acute immobilization stress following contextual fear conditioning reduces fear memory: timing is essential. Behav Brain Funct. 12(1):8 * Uwaya A. et al. (2016) Acute immobilization stress following contextual fear conditioning reduces fear memory: timing is essential. Behav Brain Funct. 12(1):8* Yasumoto Y et al. (2016) Short-term feeding at the wrong time is sufficient to desynchronize peripheral clocks and induce obesity with hyperphagia, physical inactivity and metabolic disorders in mice. Metabolism. 65(5):714-727* Youcef G et al. (2016) Preventive and chronic mineralocorticoid receptor antagonism is highly beneficial in obese SHHF rats. Br J Pharmacol. 173(11):1805-1819.* Beaulieu M et al. (2017) Socially-induced variation in physiological mediators of parental care in a colonial bird. Horm Behav. 93:39-46* Chen L et al. (2017) Preventive effects of ginseng total saponins on chronic corticosterone?induced impairment in astrocyte structural plasticity and hippocampal atrophy. Phytother Res. 31(9):1341-1348* Homma T et al. (2017) Heightened aggressive behavior in mice deficient in aldo-keto reductase 1a (Akr1a). Behav Brain Res. 319:219-224* Morozumi N (2017) Medicine against growth failure induced by administration of steroid. Patent Application Publication No: US 2017/0080049 A1. Mar. 23, 2017* Oishi K et al. (2017) Feeding cycle-dependent circulating insulin fluctuation is not a dominant Zeitgeber for mouse peripheral clocks except in the liver: Differences between endogenous and exogenous insulin effects. Biochem Biophys Res Commun. 483(1):165-170.* Tam SK et al. (2017) Constant Light Desynchronizes Olfactory versus Object and Visuospatial Recognition Memory Performance. J Neurosci. 37(13):3555-3567* Tsunokuma N et al. (2017) Depletion of Neural Crest-Derived Cells Leads to Reduction in Plasma Noradrenaline and Alters B Lymphopoiesis. J Immunol. 198(1):156-169 * Villareal MO et al. (2017) Anti-stress and neuronal cell differentiation induction effects of Rosmarinus officinalis L. essential oil. BMC Complement Altern Med. 17(1):549.* Wada M et al. (2017) Circadian clock-dependent increase in salivary IgA secretion modulated by sympathetic receptor activation in mice. Sci Rep. 7(1):8802* Oishi K et al. (2018) Chronic sleep disorder induced by psychophysiological stress induces glucose intolerance without adipose inflammation in mice. Biochem Biophys Res Commun. 495(4):2616-2621* Yoshida S et al. (2018) Corticotropin-Releasing Factor Receptor 1 in the Anterior Cingulate Cortex Mediates Maternal Absence-Induced Attenuation of Transport Response in Mouse Pups. Front. Cell. Neurosci. 12: 1-14.* Chu H et al. (2019) Sleep deprivation modifies noise-induced cochlear injury related to the stress hormone and autophagy in female mice. Front Neurosci. 13:1297* Gao C et al. (2019) Antidepressive Effects of Taraxacum Officinale in a Mouse Model of Depression Are Due to Inhibition of Corticosterone Levels and Modulation of Mitogen-Activated Protein Kinase Phosphatase-1 (Mkp-1) and Brain-Derived Neurotrophic Factor (Bdnf) Expression. Med Sci Monit. 25: 389?394* Nakao R et al. (2019) Ketogenic diet induces skeletal muscle atrophy via reducing muscle protein synthesis and possibly activating proteolysis in mice. Sci Rep. 9(1):19652.* Rettig TA et al.(2019) Effects of skeletal unloading on the antibody repertoire of tetanus toxoid and/or CpG treated C57BL/6J mice. PLOS ONE images/Assaypro/article January 17, 2019* Terao R et al. (2019) Immunostimulatory effect of kumquat (Fortunella crassifolia) and its constituents, beta-cryptoxanthin and R-limonene. Food Funct. 10(1):38-48. * Tung TH et al. (2019) Fish Oil, but Not Olive Oil, Ameliorates Depressive-Like Behavior and Gut Microbiota Dysbiosis in Rats under Chronic Mild Stress. Biomolecules 9(10):10.3390/biom9100516* Wilcox AG (2019) Circadian characterisation of the transcription factor Zfhx3 utilising a conditional mutagenesis approach. University of Oxford. Ph.D. Thesis (Corticosterone kit)* Campos P et al. (2020) Diving into the brain: deep-brain imaging techniques in conscious animals. J Endocrinol. pii: JOE-20-0028.R1. doi: 10.1530/JOE-20-0028
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Horizon Dx RS (Reference Standard )标准品常见问题汇总Q-Seq HDx RS 1 什么是Q-Seq HDx 标准品?答:Q-Seq HDx标准品是通过精准基因编辑具有多种突变位点分子诊断检测标准参照物,可直接应用于各种高通量分子诊断平台,如:NGS, QPCR, ddPCR。其主要用途为评价每次检测突变特异性和灵敏度以灵敏度的精确确认。2 Q-Seq HDx 标准品是如何制作出来的?答:通过提取自人的... 查看更多>
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121700-26-3标准品对照品是由上海远慕生物科技有限公司代理或销售的上海远慕品牌的试剂,产品来源于进口/国产。上海远慕生物科技有限公司是中国最权威的121700-26-3标准品对照品试剂销售服务商之一,在上海等地方销售121700-26-3标准品对照品试剂已经多年。生物在线为您提供众多企业121700-26-3标准品对照品仪器产品及图片,以便挑选到性价比高,合适的121700-26-3标准品对照品产品 查看更多>
木葡聚糖 xyloglucan DP7 (XFG,Non-reduced end.) 木葡七糖(XFG) 1mg100% xyloglucan oligosaccharides(苹果来源) 100%低聚木葡糖混标 100mgxyloglucan DP6(XLG) 木葡六糖(XLG) 10mgAcetylated xyloglucan DP6 (Ac-XLG) 乙酰化木葡六糖(Ac-XLG) 10mgxyloglucan DP7 (XFG,Non-reduced end.) 木葡七糖(XFG) 10mgRe 查看更多>
上海子起生物科技有限公司在发布的WAKO高度密封瓶用于储存挥发性溶剂标准品供应信息,浏览与WAKO高度密封瓶用于储存挥发性溶剂标准品相关的产品或在搜索更多与WAKO高度密封瓶用于储存挥发性溶剂标准品相关的内容。 查看更多>
上海广锐生物科技有限公司在发布的维生素C价格标准品对照品价格供应信息,浏览与维生素C价格标准品对照品价格相关的产品或在搜索更多与维生素C价格标准品对照品价格相关的内容。 查看更多>
甲胎蛋白AFP标准品太好用了!甲胎蛋白(AFP)National Standard Material of Alpha Fetoprotei 查看更多>
常见问题
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商品咨询
不属于危险品,危险品是指易燃易爆的。色素属于致癌物。

请问各位大侠,我用两家公司相同指标的时候,尽管灵敏度比较一致,A公司的标准品在B公司的试剂盒检测不出来或者OD值差别特别大,是什么原因?还请各位大侠不吝赐教,**

sigma标准品,网站介绍说明(analytical standard).sigma提供标准品都证书 . 除外产品,都高纯试剂.用做照,定性.做

因为一致性评价BE的原因,需要用到一个代谢产物的标准品,该标准品没有市售合法来源,也没有EP/USP等类别的销售,我们自己完成了制备。有几个问题咨询一下群里的分析专家:(1)企业自行标化行不行?咨询省药检院,此标准品只能委托国际上权威的标准品供应商标化,并出具标化报告,自己标化不算数。由于没有溯源的权威标准品,省药检院不承接标化;(2)有没有人对国外默克、sigma等公司做过委托标化的业务,或者有其他药监部门认可的服务公司?(3)此种用途的标准品的含量要求是不是需要≥99.5%?(4)群友们有没有其他的解决方式?





标准品应该用十万分之一的天平称量,应该最低称量多少?如果是浓度为10ug/ml的标准品又应该怎么称量?
什么是标准品CRM和对照品RM123
暮晨爱小念xf52017-10-12
Certified Reference Materials (CRM)
Reference material, accompanied by a certificate, one or more of whose property values are certified by a procedure, which established its traceability to an accurate realization of the unit in which the property values are expressed, and for which each certified value is accompanied by an uncertainty at a stated level of confidence. (Brammer StandardBASARMIetc). (ISO Guide 30-1992)
标准品CRM:标准物质/标准品附带析证书属性值某项或若干项都按照某程序进行验证验证程序建立些属性值所表述体系精确体现追溯性每经验证数值都伴随着某特定置信水平确定度(BS,NISTBASARMI等)(ISO Guide 30-1992)
Reference Materials(RM)
Materials or substance one or more of whose property values are sufficiently homogeneous and well established to be used for the calibration of an apparatus, the assessment of a measurement method, or for assigning values to materials. (ISO Guide 30-1992)
照品RM:种原料或物质其某种或几种属性值表现充均性并且用于设备校准析评估或者物质定植(ISO Guide 30-1992)

本人非分析化学专业学生,但是最近可能要用到高效液相的强大功能来做动物组织糖皮质激素的检测。

想请问各位专家,做高效液相时,标准品和对照品各是什么?我都需要购买吗?

先谢谢有心人的解答!

LGC、USP、EP、TRC、DR、cerilliant、英药典、witega、chromadex等找广州优瓦产品齐全价格优惠
检所买自制单位要检查用或者溯源性要求检所没都外面公司其实代售些单位给您购买省您家单位跑疑问问我北京捷诚科远化工技术研究院您服务与想要产品
用于药品研究和用于药品检验的对照品,标准品就是药品标准物质。

药品标准物质由中国药品生物制品检定所负责标定。中国药品生物制品检定所可以组织有关的省、自治区、直辖市药品检验所、药品研究机构或者药品生产企业协作标定国家药品标准物质。
药品标准物质分类包括:标准品、对照品、对照试剂、对照制剂、对照药材、标准量具或耗材、工作标准品、精品。
如果你需要购买 药品对照品、标准品,可以到中国药品生物制品检定所订购,也可以查询中国标准物质网订购。
1、纯度纯度即原药中有效成份的含量,以百分率表示。纯度是原药质量的主要指标,有效成分含量百分率越高质量越好。联合国粮农组织(FAO)和世界卫生组织(WHO)公布的农药原药质量标准,纯度应在90%以上。在我国的农药质量标准中,原药的纯度一般也能达到90%以上。纯度低的农药原药中杂质的含量就高,原药中杂质过多有以下害处:(1)可能会对作物产生药害。2000年在吉林省梅河口市稻田使用苄嘧磺隆出现药害,造成稻苗死亡。苄嘧磺隆对稻苗的安全性较好,一般不会产生药害。据初步研究表明:产生药害的原因是苄嘧磺隆中的杂质JP-003和JP-004含量超标。(2)杂质较多会增高原药对人的毒性。例如甲胺磷的纯品对大鼠的LD50为30毫克/千克体重,而国内有的厂家生产的50%甲胺磷乳油对大鼠的LD50为13.6毫克/千克,说明毒性增高,其原因为甲胺磷原油中有5种杂质的含量较高,而且这5种杂质的毒性也较甲胺磷纯品的毒性为高。(3)原药中杂质都对以有效成分分子中含有某元素或某原子团的量计算有效成分含量的化学分析法失去原有的准确度。由于杂质中同样含有与有效成分相同的元素或原子团,使测定的结果产生偏差,不能反映原药及其制剂中有效成分的真实含量。(4)原药中的杂质还给加工粉剂带来困难,因为杂质的存在使原药的凝固点下降,不易粉碎。(5)原药的杂质能降低有效成分的稳定性,而且随着农药的使用,杂质进入环境之中,造成污染。所以要尽可能提高原药的纯度,减少杂质的含量。
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