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Tocris/DLPC/4378/50/50 mg
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Tocris/DLPC/4378/50/50 mg
品牌 / 
Tocris
货号 / 
4378/50
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4000-520-616
Description:LRH-1agoNIST;regulatesbileacidmetabolism
ChemicalName:(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveagonistoftheorphannuclearreceptorLRH-1(liverreceptorhomolog-1,NR5A2)invitro.Inducesbileacidbiosyntheticenzymes;increasesbileacidanddecreaseshepatictriglyceridesandserumglucose.Exhibitsantidiabeticeffects.

TechnicalData

M.Wt621.83
FormulaC32H64NO8P
StorageStoreat-20°C
CASNumber18194-25-7
PubChemID512874
InChIKeyIJFVSSZAOYLHEE-SSEXGKCCSA-N
Smiles[O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
ethanol62.18100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight621.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.61mL8.04mL16.08mL
5mM0.32mL1.61mL3.22mL
10mM0.16mL0.8mL1.61mL
50mM0.03mL0.16mL0.32mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet