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Description:LRH-1agoNIST;regulatesbileacidmetabolism
ChemicalName:(7R)-4-Hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxododecyl)oxy]-3,5,9-trioxa-4-phosphaheneicosan-1-aminium-4-oxide
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
SelectiveagonistoftheorphannuclearreceptorLRH-1(liverreceptorhomolog-1,NR5A2)invitro.Inducesbileacidbiosyntheticenzymes;increasesbileacidanddecreaseshepatictriglyceridesandserumglucose.Exhibitsantidiabeticeffects.
TechnicalData
M.Wt | 621.83 |
Formula | C32H64NO8P |
Storage | Storeat-20°C |
CASNumber | 18194-25-7 |
PubChemID | 512874 |
InChIKey | IJFVSSZAOYLHEE-SSEXGKCCSA-N |
Smiles | [O-]P(OC[C@H](OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O)(OCC[N+](C)(C)C)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
ethanol | 62.18 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight621.83.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.61mL | 8.04mL | 16.08mL |
5mM | 0.32mL | 1.61mL | 3.22mL |
10mM | 0.16mL | 0.8mL | 1.61mL |
50mM | 0.03mL | 0.16mL | 0.32mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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