![]() | CatalogNo.: S-100B MW: 540.8 CAS: 752987-57-8 Description: Echelonoffersauniqueselectionofsphingosineanalogslabeledattheterminusofthealkylchainwithbiotinorfluorescentgroups.Allcompoundsaresynthesizedfromchiralprecursorsandareavailableaslyophilizedpowders. Echelon'salkyl-labeledsphingosinesaresynthesizedwiththenaturalerythrostereochemistryandmaintainsimilarpropertiesassphingosine.Forexample,labeledsphingosinesarephosphorylatedbysphingosinekinases(1&2)andcanbeusedinhighthroughputscreeningapplications.Inaddition,theyinduceaNiemanPicktypeC1diseasecellularphenoypeinRAWmacrophagesinthesamemannerasexogenouslyaddedsphingosine. | ||
StorageSphingosine-biotinisrelativelystableatroomtemperatureasasolid.Itisbeststoredasadriedsolid,protectedfromlightat-20ºC.Solutions/emulsionsshouldbekeptat-20ºC.SolubilityMeOH>1mg/ml | |||







