| ProductName | Cat# | Clone# | Isotype | Applications | Reactivity | Unit/Size |
| Anti-HumanCD11aMonoclonalAntibody(BiotinConjugated) | E-AB-1536 | MouseIgG1 | FCM* | Human | 25μg,100μg |
Description
CD11aisa170-180kDtypeItransmembraneglycoproteinalsoknownasLFA-1αchainandintegrinαLsubunit.CD11anon-covalentlyassociateswithintegrinβ2(CD18)toformLFA-1.Itisexpressedonallleukocytes,includingBandTlymphocytes,monocytes,macrophages,neutrophils,basophilsandeosinophils.Itisabsentonnon-hematopoietictissuesandplatelets.CD11aplaysacentralroleinleukocytecell-cellinteractionsandisimportantinlymphocytecostimulation.CD11a/CD18bindstoICAM-1(CD54),ICAM-2(CD102),andICAM-3(CD50).
SpecSheetE-AB-1536(PDFFile)
| Synonyms | |
| Concentration | 1mg/mL |
| Host | Mouse |
| Immunogen | |
| PurificationMethod | |
| Formulation | PBSwith0.09%NaN3,0.2%BSA,PH7.2 |
| Storage | Keepasconcentratedsolution.Storeat4°Candprotectedfromprolongedexposuretolight.Donotfreeze. |
| Dilution |
Cautionmustbetakentoavoidcontactwithskinoreyes.Insuchacase,rinsethoroughlyatoncewithwater.Donotingest,inhale,orswallow.Seekmedicalattentionimmediately.Wearappropriateprotectiveclothingsuchaslaboratoryoveralls,safetyglassesandgloves.Itisstronglyadvisedthatthisproductshouldbehandledbypeoplewhohavebeenwelltrainedinlaboratorytechniquesandthatitishandledwithcarepursuanttotheprinciplesofgoodlaboratorypractice.Allchemicalsaredeemedpotentiallyharmful.Thevialispronetofallover.Usecaution,especiallywhenthelidisoff.
FORRESEARCHUSEONLY,NOTFORUSEINDIAGNOSTICPROCEDURES.
*RemarkIcon:
WB=WesternBlotting,IP=Immunoprecipitation,IF=Immunofluorescence,IHC=Immunohistochemistory,IHC-p=ImmunohistochemistoryParaffin,FCM=FlowCytometry,CH=ChIPAssay
Manufacturedby:Elabscience
ebiomall.com
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抗人球蛋白试验，又称Coombs’试验，是诊断自身免疫性溶血性贫血(AIHA)的重要依据。
正常人直接与间接试验均为阴性，Coombs’试验阴性有时并不能排除AIHA
