Lyophilized Powder This product is freeze dried. All water molecules have been removed.
Bioassay Tested Every lot is tried & tested in a relevant biological assay.
Our Bioassay
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- Traynelis, S.F. et al. (2010) Pharmacol. Rev. 62, 405.
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Alomone Labs (RS)-AMPA activates GluA1 channels expressed in Xenopus oocytes.Time course of current reversible activation by 1, 10 and 100 μM (RS)-AMPA (#A-265) followed by glutamate elicited currents (100 μM, holding potential -80 mV), for comparison.
- 1. Howes, J.F. and Bell, C. (2007) Neurotherapeutics 4, 126.
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Glutamate is the main excitatory neurotransmitter in the CNS. It is also involved in a variety of pathological conditions including epilepsy. Glutamate binds to a number of different receptor types such as the AMPA, kainate and NMDA receptors that relay its excitatory activity.
(RS)-AMPA is a synthetic AMPA receptor agonist. It has an effective concentration of 0.1-100 µM. RS-AMPA selectively binds to AMPA receptors over the other types of glutamate receptors. RS-AMPA was found to elicit feeding behavior in a rat model while RS-AMPA’s enantiomer did not produce similar results1.
(RS)-AMPA (#A-265) is a highly pure, synthetic, and biologically active compound.
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抗人球蛋白试验,又称Coombs’试验,是诊断自身免疫性溶血性贫血(AIHA)的重要依据。
正常人直接与间接试验均为阴性,Coombs’试验阴性有时并不能排除AIHA


