LyophilizedPowderThisproductisfreezedried.Allwatermoleculeshavebeenremoved.
BioassayTestedEverylotistried&testedinarelevantBIOLOGicalassay.
OurBioassay
- Bjerrum,E.J. etal.(2003) J.Med.Chem. 46, 2246.
- 1.Bjerrum,E.J. etal.(2003) J.Med.Chem. 46, 2246.
- 2.Guntupalli,S. etal. (2016) NeuralPlast. 2016, 3204519.
Cl-HIBO(chloro-homoibotenicacid)actsasafullagonistatAMPAreceptors(AMPARs).Cl-HIBOisthemostselectiveagonistreportedto-dateforGluR1/2.Thus,thecompoundisconsideredtobeavaluabletoolforstudyingthebiologicalbehavioranddistributionofAMPARs1.
TheionotropicglutamateAMPAreceptorsaretheprimaryreceptorsthatmediatefastexcitatorysynaptictransmissioninthemammalianbrain.Themajorityofthistransmissioninthemammaliancentralnervoussystemismediatedbythereleaseofglutamatefromthepresynapticterminalanditsbindingtoglutamatereceptorsonthepostsynapticmembrane2.
Cl-HIBO(#C-355) isahighlypure,synthetic,andbiologicallyactivecompound.
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抗人球蛋白试验,又称Coombs’试验,是诊断自身免疫性溶血性贫血(AIHA)的重要依据。
正常人直接与间接试验均为阴性,Coombs’试验阴性有时并不能排除AIHA



