
Serum-SalivaCorrelation | NA |
Sensitivity | 1pg/mL |
SampleTestVolume | 100μL |
RecommendedCollectionVolume | 225μL* |
SpecialConsiderations | No |
CollectionProtocol | DownloadPDF |
Estrone(3-hydroxy-1,3,5(10)-estratrien-17-one;E1)isoneofthethreemainestrogenicsteroidhormonesproducedinhumans.Circulatingestronelevelsarerelativelyhighatbirthinbothmalesandfemales,decreasepostnatally,andincreaseduringpuberty.(1)Ofthethreemajorestrogens,estroneispredominantaftermenopauseinwomen.(1)
Inpremenopausalwomenestroneisprimarilyproducedbyconversionofandrostenedioneintheovaries,withconcentrationspeakinginthepreovulatoryphaseandasmallersecondaryincreaseduringthelutealphase.(1,2)Inpost-menopausalwomen,children,andmen,estroneislargelyproducedbyconversionofandrostenedioneinperipheraltissues.(1,2,3)EstroneissubsequentlyreducedtoestrADIolinvariousperipheraltissues.(3)
Innon-pregnantwomen,onlyabout3%ofestroneinthebloodstreamisnotboundtoproteins.(4)Unboundestroneenterssalivafrombloodviaintracellularmechanisms,andinsalivathemajorityoftheestroneremainsunboundtoprotein.Thesalivaandplasmavaluesarehighlycorrelated.(5)
- Faiman,C.,Winter,J.S.,Reyes,F.I.(1976).Patternsofgonadotrophinsandgonadalsteroidsthroughoutlife.ClinObstetGynecol,3(3),467-83.
- Cañez,M.S.,Lee,K.J.,&Olive,D.L.(1992).Progestogensandestrogens.Infert ReprodMedClinNorthAmer,3,59-78.
- Sasano,H.,Harada,N.(1998).Intratumoralaromataseinhumanbreast,endometrial,andovarianmalignancies. EndocrRev,19(5),593-607.
- Speight,A.C.,Hancock,K.W.,Oakey,R.E.(1979). Non-protein-boundoestrogensinplasmaandurinaryexcretionofunconjugatedoestrogensinnon-pregnantwomen. JEndocrinol,83,385-91.
- Vining,R.F.,McGinley,R.A.(1987).Themeasurementofhormonesinsaliva:Possibilitiesandpitfalls. JSteroidBiochem,27(1-3),81-94.
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(1)优级纯试剂 亦称保证试剂,为一级品,纯度高,杂质极少,主要用于精密分析和科学研究,常以GR表示。
(2)分析纯试剂 亦称分析试剂,为二级品,纯度略低于优级纯,杂质含量略高于优级纯,适用于重要分析和一般性研究工作,常以AR表示。
(3)化学纯试剂 为三级品,纯度较分析纯差,但高于实验试剂,适用于工厂、学校一般性的分析工作,常以CP表示。
(4)实验试剂 为四级品,纯度比化学纯差,但比工业品纯度高,主要用于一般化学实验,不能用于分析工作,常以 LR表示。
以上按试剂纯度的分类法已在我国通用。根据化学工业部颁布的“化学试剂包装及标志”的规定,化学试剂的不同等级分别用各种不同的颜色来标志,见表1。
表1 我国化学试剂的等级及标志
bhclna2so4nano3na2co3
chclnaohna2co3nacl
dba(oh)2nahco3alcl3nahso4
刚入这行,谢谢大家
A.H2SO4Na2SO4AgNO3BaCl2.
B.NaOHNa2CO3NaHSO4MgCl2
C.CaCl2NaNO3MgSO4BaCl2
D.HNO3KOHKClK2CO3


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