
Description: | This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples. |
Type: | AssayMax ELISA Kits |
Samples: | Serum Plasma Cell Culture Urine Saliva Milk CSF |
Catalog Number: | EA2500-7 |
Species: | Human |
Format: | Sandwich ELISA |
Size: | 96 Well Plate |
Range: | 0.391 - 25 ng/ml |
Research Area: | Diabetes, Nephrotic Syndrome, Heart Disease, Metabolism, Cancer, Hypoxia |
Entrez Gene: | 9370 |
Omim: | 605441 |
UniProt: | Q15848 |
Unigene: | Hs.80485 |
Synonyms: | Adiponectin, AdipoQ, ACDC, ACRP30, APM1, GBP28,Adipocyte, C1q and Collagen Domain-containing Protein, 30 kDa Adipocyte Complement-related Protein |
Note: | For Research Use Only, Not To Be Used For Diagnostic Purposes |
Product References: | *Norata GD et al. (2007) Leptin:Adiponectin Ratio Is an Independent Predictor of Intima Media Thickness of the Common Carotid Artery. Stroke 38(10):2844-2846 *Goymen A et al. (2008) Comparison of Maternal Serum Adiponectin and Leptin Measurements in Screening and Diagnosis of Gestational Diabetes Mellitus.Perinatal Journal 16(3):92-99*Goymen A et al. (2008) The Role of Maternal Serum Adiponectin Levels in Screening and Diagnosis of Gestational Diabetes Mellitus.Perinatal Journal 16(2):49-55 *DIKMEN E et al. (2010) Plasma adiponectin and resistin levels in women with polycystic ovary syndrome: relation to body mass index and insulin resistance. Turk J Med Sci 40(1):1-7*Hsueh KC et al. (2010) Serum leptin and adiponectin levels correlate with severity of allergic rhinitis. Pediatr Allergy Immunol. 21(1 Pt 2):e155-159*Lau CH et al. (2010) The novel adiponectin-resistin (AR) and insulin resistance (IRAR) indexes. Nature Preceedings. 4191:1-235*Perreault L et al. (2010) Altered Intramuscular Lipid Metabolism Relates to Diminished Insulin Action in Men, but Not Women, in Progression to Diabetes. Obesity. 18(11):2093-100* Tarkun I et al. (2010) Impact of treatment with metformin on adipokines in patients with polycystic ovary syndrome. Eur. Cytokine Netw. 21(4): 272-7*Wahab F et al. (2010) Effect of Peripheral Kisspeptin Administration on Adiponectin, Leptin, and Resistin Secretion Under Fed and Fasting Conditions in the Adult Male Rhesus Monkey (Macaca mulatta). Horm Metab Res. 42:570-574*Ou HY et al. (2011) Elevated Retinol Binding Protein 4 Contributes to Insulin Resistance in Spontaneously Hypertensive Rats. Horm Metab 43(5):312-318 *Seker M et al. (2011) Tissue and Serum Adiponectin Levels in Patients with Gastric Cancer: Are there any Correlations between Adiponectin Levels and Histopathological Variables? Hepatogastroenterology. 58:110-111*Abd El-Mohsin et al. (2012) How Adiponectin Correlates with Desease Duration and Atherogenic Indices in Type 1. Diabetes, Stoffwechsel und Herz, 21:7-12*Ersan F et al. (2012) Prediction of metabolic syndrome in women with polycystic ovary syndrome. J Turkish-German Gynecol Assoc 13: 178-83 *Hashim AA (2012) How Adiponectin Correlates with Desease Duration and Atherogenic Indices in Type 1. Diabetes Stoffw Herz 21: 7-12*Ou HY et al. (2012) Endoplasmic reticulum stress induces the expression of fetuin-A to develop insulin resistance.Endocrinology. 153(7):2974-84*Ou HY et al. (2012) Increased Fetuin-A Concentrations in Impaired Glucose Tolerance with or without Nonalcoholic Fatty Liver Disease, But Not Impaired Fasting Glucose. J Clin Endocrinol Metab. 97(12):4717-23* Sadik NAH et al. (2012) The significance of serum levels of adiponectin, leptin, and hyaluronic acid in hepatocellular carcinoma of cirrhotic and noncirrhotic patients. Hum Exp Toxicol. 31(4):311-21*Volat FE et al. (2012) Depressed Levels of Prostaglandin F2alpha in Mice Lacking Akr1b7 Increase Basal Adiposity and Predispose to Diet-Induced Obesity. Diabetes. 61(11): 2796-2806*Baragetti I et al. (2013) -374 T/A RAGE Polymorphism Is Associated with Chronic Kidney Disease Progression in Subjects Affected by Nephrocardiovascular Disease. PLoS One 8(4):e60089*Marcelino H et al. (2013) A Role for Adipose Tissue De Novo Lipogenesis in Glucose Homeostasis During Catch-up Growth: A Randle Cycle Favoring Fat Storage. Diabetes. 62(2):362-372*Marcelino H et al. (2013) A Role for Adipose Tissue De Novo Lipogenesis in Glucose Homeostasis During Catch-up Growth: A Randle Cycle Favoring Fat Storage. Diabetes. 62(2):362-372*Motawi TMK et al. (2013) Naproxen and Cromolyn New Glycogen Synthase Q1 Kinase 3beta Inhibitors for Diabetes and Obesity: An Investigation by Docking Simulation and Subsequent In Vitro/In Vivo Biochemical Evaluation. J Biochem Molecular Toxicology. June 4, 2013. DOI 10.1002/jbt* Ou HY et al. (2015) Both diabetes and fetuin-A are independently associated with increased risk of arterial stiffness. Clin Chim Acta. 445:133-8* Stoppeler S et acl. (2013) Gender and strain-specific differences in the development of steatosis in rats. Laboratory Animals. 47:43-52* Yu DM (2013) Adipokines level and insulin resistance in abdominally obese patients with acute ischemic lecunar strokes. CyberLeninka The world of medicine and biology*Barghash AA et al. (2014) Adipose tissue cytokines: Relation to glycemic control, insulin resistance and biochemical bone markers in type 2 diabetic Saudi male patients. Journal of Taibah University Medical Sciences. 9 (2): 151-157 *Huma T et al. (2014) Peripheral administration of kisspeptin antagonist does not alter basal plasma testosterone but decreases plasma adiponectin levels in adult male rhesus macaques. Turkish Journal of Biology 38:450-456*Sultana M et al. (2014) Association of Serum Adiponectin in the Development of Type 2 Diabetes Mellitus in Bangladesh. World J. Med. Sci. 11(2):248-254 *Yen M et al. (2014) Association of fetuin A, adiponectin, interleukin 10 and total antioxidant capacity with IVF outcomes. Iran J Reprod Med 12(11):747-754*Ergin S et al. (2015) The role of adenovirus 36 as a risk factor in obesity: The first clinical study made in the fatty tissues of adults in Turkey. Microbial Pathogenesis 80(2015):57-62*Huang CF et al. (2015) Arsenic Exposure and Glucose Intolerance/Insulin Resistance in Estrogen-Deficient Female Mice. Environ Health Perspect. 2015 Apr 10.*Mohamed AA et al. (2015) Reduction of Plasma Adiponectin in Egyptian Obese Children with Nonalcoholic Fatty Liver Disease. International Journal of Biochemistry Research & Revies. 5(4)P:225-232* Pala HG et al. (2015) Adiponectin Levels in Gestational Diabetes Mellitus and in Pregnant Women Without Glucose Intolerance. Adv Clin Exp Med. 24(1): 85-92* Ahmed S and Jahan S (2016) Possible Role of Neuromedin S (NMS) in Male Reproduction: Effect of NMS on Adipokines Secretion in Male Rhesus Monkeys (Macaca mulatta). Pakistan J. Zool., 49 (1):273-279 * Bilir BE et al. (2016) The effects of fat distribution and some adipokines on insulin resistance in subjects with prediabetes. Endokrynologia Polska 67 (3):277-282 * Cerman AA et al. (2016) Dietary glycemic factors, insulin resistance, and adiponectin levels in acne vulgaris. J Am Acad Dermatol. 75(1):155-62* Elsahy KI et al. (2016) Leukocytes apoptosis and adipocytokines in children with beta thalassemia major. Clin Exp Med. 16(3):345-350.* Gul E et al. (2016) The Diagnostic Role of Adiponectin in Pulmonary Embolism. Biomed Res Int. 2016;2016:6121056 * Hashim AA et al. (2016) CTX Correlation to Disease Duration and Adiponectin in Egyptian Children with T1DM. J Med Biochem. 35(1):34-42 * Tsyplenkova HC et al. (2016) Heart rate features among men of working age with obesity and hypertension. Obesity and metabolism. 13 (1): 30-35* Yurieva AV et al. (2016) DYNAMICS OF LEVELS OF SOME ADIPOKINS IN CHILDREN WITH OBESITY UNDER INFLUENCE OF SANATORIUM-RESORT TREATMENT. Bulletin of physiotherapy and balneology.* Abdel-Fadeil MR et al. (2017) Obstructive sleep apnea: Influence of hypertension on adiponectin, inflammatory markers and dyslipidemia. Pathophysiology 24:305?315.* Kahraman R et al. (2017) Are adipocytokines inflammatory or metabolic mediators in patients with inflammatory bowel disease? Therapeutics and Clinical Risk Management. 13:1295-1301* Shevchuk SV et al. (2018) ADIPOKINE LEVELS IN PATIENTS WITH RHEUMATOID ARTHRITIS, ASSOCIATION WITH DISEASE COURSE AND CARDIOVASCULAR DISEASE. Rheumatology 72(2): 35-39.* Farid W et al. (2019) The correlation between serum adiponectin levels and severity of coronary artery disease. Menoufia Medical Journal. 32(1):181-186* Jain NB et al. (2019) Correlation of C1q/TNF-Related Protein-3 with Cardiac Autonomic Tone and Metabolic Parameters in Obesity. Int J Endocrinol Metab. 17(2):e74250* Pebehko HA (2019) Effectiveness of sanatorium-resort treatment in rehabilitation of children with arterial hypertension and metabolic disorders. Bulletin of Physiotherapy and Balneology* Shokouh P et al. (2019) Efficacy of Arabica Versus Robusta Coffee in Improving Weight, Insulin Resistance, and Liver Steatosis in a Rat Model of Type-2 Diabetes. Nutrients. 11(9). pii: E2074 |
ebiomall.com






>
>
>
>
>
>
>
>
>
>
>
>
往常一直用“猴年马月”来形容时间的漫长,来看看我们身边与“猴”相关的药物物种都有哪些呢?您最熟悉的是什么?
今天逛超市,印象最深的是据说有“抗癌”作用的猴头菌,来看看它的功效有哪些
《全国中草药汇编》:猴头菌
【药材名称】猴头菌
【别名】猴头、刺猬菌、猬菌
【来源】真菌类担子菌纲多孔菌目齿菌科猴头菌Hericiumerinaceus(Bull.exFr.)Pers.,以子实体入药。
【生境分部】生于栎、胡桃等阔叶树种的立木及腐木上。
【性味】甘,平。
【功能主治】利五脏,助消化。主治消化不良,神经衰弱、身体虚弱。
【用法用量】消化不良:猴头菌2两,水浸软,切成薄片,水煎服,日服2次,黄酒为引。
神经衰弱、身体虚弱:猴头菌(干品)5两,切片与鸡共煮食用,日服1次(或用鸡汤煮食)。
【备注】(1)据文献,本品子实体内含抗癌物质。
(2)还有一种小刺猴头菌Herieiumcaptmedusae(Bull.exFr.)Pers.,刺密而短,效用同猴头菌。
【摘录】《全国中草药汇编》
下面是《中华本草》的记载:
【药理作用】1.增强免疫功能
同基因骨髓移植55d后,受体小鼠免疫功能严重损害。脾细胞产生白介素-2(IL-2)能力等细胞免疫功能明显低下,连续腹腔注射猴头菌多糖和胸腺肽15d后,小鼠脾细胞产生IL-2能力及对刀豆素A(Con
A)刺激的增殖反应和混合淋巴细胞培养反应,均显着增强。说明猴头菌多糖与胸腺肽合用比单独使用胸腺肽更能明显促进同基因骨髓移植小鼠免疫功能的早期恢复。猴头菌多糖给小鼠腹腔注射2mg/只,连续7d,能明显提高小鼠腹腔巨噬细胞的吞噬功能;可促进溶血素生成,增加体液免疫的能力。若给小鼠腹腔注射2.88mg/只,连续8d,则可明显对抗由环磷酰胺中毒所引起的白细胞下降,下降率仅为对照组的一半。猴头菌多糖在体外对由ConA活化的小鼠胸腺细胞有较强的促进增殖作用,也可促进脾淋巴细胞的增殖,并对脂多糖(LPS)刺激的B细胞也有协同作用。
2.抑瘤作用在Swiss雄性小鼠左前腋皮下,接种肉瘤S180细胞,然后口服猴头菌多糖50mg/kg,100mg/kg,200mg/kg,每日1次,连续7d,结果表明,3个剂量组对荷瘤生长均有抑制作用;对自然杀伤(NK)细胞活性有明显的激活作用;荷瘤重量与其相应鼠脾NK细胞活性呈负相关猴头菌还能抑制黄曲霉素对大鼠的致肝癌作用,减少肝切面的病灶数。
3.抗溃疡作用及降血糖作用通过胃蛋白酶抑制吸附实验,证明猴菇菌片治疗胃溃疡的作用机制,可能是由于抑制胃蛋白酶活性而促进溃疡愈合。猴头菌多糖可降低小鼠正常血糖和四氢嘧啶所致糖尿病小鼠的血糖水平。
4.延缓衰老作用猴头菌丝体多糖和子实体多糖能显着增加果蝇飞翔能力,降低刚孵化果蝇和小鼠心肌组织脂褐质含量,并能增加小鼠脑和肝脏中超氧化物歧化酶(SOD)的比活力。
【性味】甘;平
【归经】入脾、胃经
【功能主治】健脾养胃;安神;抗癌。主体虚乏力;消化不良;失眠;胃与十二指肠溃疡;慢性胃炎;消化道肿瘤
【用法用量】内服:煎汤,10~30g,鲜品30~100g;或与鸡共煮食。
【各家论述】1.《临海水土异物志》:民皆好啖猴头羹,虽五肉臛不能及之,其俗言:宁负千石之粟,不愿负猴头羹CONG。
2.《农政全书》:如无花、麻姑、猴头之属,皆草木根腐坏而成者。
3.《新华本草纲要》:全草:味甘,性平。有利五脏、助消化、滋补、抗癌等功能。与本品有类似功效,且分布区相近似的尚有以下两个近缘种:玉髯
H.Coralloides(Scop.Fr.)Pers,exGtay及分枝猴头菌H.ramosum(Bull.Ex
Merat。)Letellier.
找了张照片,猴头菇哦
中新网2月26日电据美联社报道,科学家称已经***了猴子抵抗艾滋病毒感染的机密。这是一个让人欣喜的重大发现,因为接下来的研究很可能发现一个人类预防艾滋病的新策略。
某些灵长目动物可以防止艾滋病菌在体内蔓延,这一谜团困扰科学家长达10年之久,如今终于有了答案。
美国健康研究所基础科学研究室主任称,人们根据这一发现可能研制出治疗爱滋的药物,或者是预防爱滋的疫苗。“我们将立即就15个不同方向进行研究。这将是基础研究意义重大的一年,我们取得了很多的研究成果,而且很多工作还在继续。”
此项发现是由约瑟夫.缲德劳斯克博士和他领导的哈佛大学研究人员首先公布的。约瑟夫现在波士顿达纳法伯癌症研究所工作。报告结果发表在2月27日《自然》杂志上。
艾滋病毒的发病原理是病毒先进入细胞内部,强占细胞组织,并用来不断进行自我复制。但是猴子体内有一种名为TRIM5-alpha的蛋白成分,可以阻止艾滋病毒进入健康细胞后脱落自身保护层。虽然对于病毒保护层的脱落问题还有待进一步认识,但是科学家认为这是艾滋病毒感染周期的一个重要环节。
加利福尼亚大学一位研究艾滋病的微生物专家称,人类体内也有名为TRIM5-alpha的成分,但是抵抗艾滋病毒的能力远远不如猴子体内的同类成分。
哥伦比亚大学一位生物化学家称,“由于这个报告的出台,各个大学的实验室都将就此问题进行研究。”
缲德劳斯克博士称在动物身上还可能找到治疗其它病毒的成分。“我们发现的也许只是自然预防系统中的第一个例子,通过同样的方法,我们很可能找到对抗其它病毒的成分。”
艾滋病毒是一种逆转录酶病毒,它可以把基因信息写入感染细胞当中,并且进行不断的复制。所以一旦感染,就很难根除。但是逆转录酶病毒也有弱点,它们如果一开始找不到立足点的话,就会很快消亡。所以TRIM5-alpha蛋白有助于在感染的初始阶段阻止病毒的蔓延。“我们知道艾滋病毒也可以感染猴子的细胞,但是感染一开始就被控制住或者终止了。只是我们还不清楚具体的控制时间。”
11132013-Nature-Article-HIV-antibody-SHIV-comments.pdf(580.15k)
11132013-Nature-Article-HIV-antibody-SHIV.pdf(1609.99k)
11132013-Nature-Letter-HIV-antibody-SHIV.pdf(3527.33k)
如题,哪几家做定制猴抗体服务比较好的?
谢谢

