中国Tocris公司 Tocris Bioscience型号参数规格,Tocris/TPEN/4309/100/100 mg,其他,Tocris,Bio-Techne,,100 mg蚂蚁淘商城

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Tocris/TPEN/4309/100/100 mg

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Tocris

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4309/100

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4000-520-616

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Description:Cell-permeableZn²⁺chelator

ChemicalName:N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Heavymetalchelator.ReactswithbothZn-proteomeandZn-metallothionein(MT)inLLC-PK₁cells;actsasanintracellularchelatorofproteomicZn²⁺.Activitydecreasesintracellularzinclevels,andinducesapoptosisinHeLaandculturedhumanretinalpigmentepithelium(RPE)cells.Cellpermeable.

TechnicalData

M.Wt	424.54
Formula	C₂₆H₂₈N₆
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	16858-02-9
PubChemID	5519
InChIKey	CVRXLMUYFMERMJ-UHFFFAOYSA-N
Smiles	N(CC3=CC=CC=N3)(CC4=CC=CC=N4)CCN(CC2=CC=CC=N2)CC1=CC=CC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	10.61	25
	ethanol	42.45	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight424.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.36mL	11.78mL	23.55mL
5mM	0.47mL	2.36mL	4.71mL
10mM	0.24mL	1.18mL	2.36mL
50mM	0.05mL	0.24mL	0.47mL

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