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ChemicalName:2-(4-Benzyoylphenoxy)-N-[1-(phenylmethyl)-4-piperidinyl]acetamidehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
AgonistofadiponectinreceptorsAdipoR1andAdipoR2(Kdvaluesare1.8and3.1μMrespectively).ActivatesAMPKandPPARαsignaling;amelioratesinsulinresistance,dyslipidemiaandglucoseintoleranceindb/dbmice.Orallyactiveantidiabeticagent.
CompoundLibraries
AdipoRonhydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 464.98 |
Formula | C27H28N2O3.HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
CASNumber | 1781835-20-8 |
PubChemID | 78243714 |
InChIKey | TZVJQEGKRLDTHQ-UHFFFAOYSA-N |
Smiles | O=C(C2=CC=C(OCC(NC3CCN(CC4=CC=CC=C4)CC3)=O)C=C2)C1=CC=CC=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 46.5 | 100 | |
ethanol | 4.65 | 10 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight464.98.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.15mL | 10.75mL | 21.51mL |
5mM | 0.43mL | 2.15mL | 4.3mL |
10mM | 0.22mL | 1.08mL | 2.15mL |
50mM | 0.04mL | 0.22mL | 0.43mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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