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Description:Prostaglandin.Vasodilatorandantiplateletagentinvivo
AlternativeNames:PGE1,ProstaglandinE1
ChemicalName:(11α,13E,15S)-11,15-Dihydroxy-9-oxo-prost-13-en-1-oicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
ProstaglandinwithsomeselectivityforEP3andEP4receptors(Kivaluesare1.1,2.1,36,10 and33nMformouseEP3,EP4,EP1,EP2andIPreceptorsrespectively).Inhibitsplateletaggregationandisavasodilatorinvivo.
TechnicalData
| M.Wt | 354.49 |
| Formula | C20H34O5 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 745-65-3 |
| PubChemID | 5280723 |
| InChIKey | GMVPRGQOIOIIMI-DWKJAMRDSA-N |
| Smiles | CCCCC[C@H](O)/C=C/[C@@H]1[C@H](C(C[C@H]1O)=O)CCCCCCC(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 35.45 | 100 | |
| ethanol | 17.72 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight354.49.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.82mL | 14.1mL | 28.21mL |
| 5mM | 0.56mL | 2.82mL | 5.64mL |
| 10mM | 0.28mL | 1.41mL | 2.82mL |
| 50mM | 0.06mL | 0.28mL | 0.56mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet

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