Tocris神经传递素 Tocris多肽,Tocris/<em>N</em>-Arachidonylglycine/1445/25/25 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/<em>N</em>-Arachidonylglycine/1445/25/25 mg

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Tocris/N-Arachidonylglycine/1445/25/25 mg

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Tocris

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1445/25

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4000-520-616

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Description:GPR18agoNIST;endocannABInoid

AlternativeNames:NAGly

ChemicalName:N-(1-oxo-5Z,8Z,11Z,14Z-eicosatetraenyl)glycine

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPR18agonist(EC₅₀=44.5nM).Endogenousanandamide-likecompound.LacksaffinityforCB₁receptors(K_i>10μM),VR1receptors(EC₅₀>10μM)andanandamidetransporters(IC₅₀>50μM)butcauseshot-plateanalgesiainmicewhengivenorally,andsuppressestonicinflammatorypain.AlsoendogenousGlyT2inhibitor.

TechnicalData

M.Wt	361.52
Formula	C₂₂H₃₅NO₃
Storage	Desiccateat-20°C
Purity	≥98%(HPLC)
CASNumber	179113-91-8
PubChemID	5283389
InChIKey	YLEARPUNMCCKMP-DOFZRALJSA-N
Smiles	O=C(NCC(O)=O)CCCC=C/CC=C/C/C=CC/C=CCCCCC

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	ethanol	36.15	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight361.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.77mL	13.83mL	27.66mL
5mM	0.55mL	2.77mL	5.53mL
10mM	0.28mL	1.38mL	2.77mL
50mM	0.06mL	0.28mL	0.55mL

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