BiologicalActivity
Selectiveα2-adrenergicreceptorantagonist(Kivaluesare1.1,1.0,0.89,1300and6500nMforα2A,α2B,α2C,α1Aandα1Breceptorsrespectively).Brainpenetrant.
CompoundLibraries
AtipamezolehydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
| M.Wt | 248.75 |
| Formula | C14H16N2.HCl |
| Storage | DesiccateatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 104075-48-1 |
| PubChemID | 13649426 |
| InChIKey | PCCVCJAQMHDWJY-UHFFFAOYSA-N |
| Smiles | CCC2(C3=CN=CN3)CC1=CC=CC=C1C2.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 24.87 | 100 | |
| water | 24.87 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight248.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.02mL | 20.1mL | 40.2mL |
| 5mM | 0.8mL | 4.02mL | 8.04mL |
| 10mM | 0.4mL | 2.01mL | 4.02mL |
| 50mM | 0.08mL | 0.4mL | 0.8mL |
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