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Description:D2receptoragoNIST.Alsoα2agonistand5-HT3antagonist
AlternativeNames:Talipexole
ChemicalName:5,6,7,8-Tetrahydro-6-(2-propen-1-yl)-4H-thiazolo[4,5-d]azepin-2-aminedihydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
DopamineD2receptoragonist,α2-adrenoceptoragonistand5-HT3receptorantagonist.DisplaysantiParkinsonianactivity.
TechnicalData
M.Wt | 282.23 |
Formula | C10H15N3S.2HCl |
Storage | DesiccateatRT |
Purity | ≥98%(HPLC) |
CASNumber | 36085-73-1 |
PubChemID | 104870 |
InChIKey | DPQAXNSOFFYKDS-UHFFFAOYSA-N |
Smiles | Cl.Cl.NC1=NC2=C(CCN(CC=C)CC2)S1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.22 | 100 | |
ethanol | 1.41 | 5 | |
water | 28.22 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight282.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.54mL | 17.72mL | 35.43mL |
5mM | 0.71mL | 3.54mL | 7.09mL |
10mM | 0.35mL | 1.77mL | 3.54mL |
50mM | 0.07mL | 0.35mL | 0.71mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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