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Tocris/BAM 22P/1650/1/1 mg
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Tocris/BAM 22P/1650/1/1 mg
品牌 / 
Tocris
货号 / 
1650/1
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Description:OpioidreceptoragoNIST.Alsoagonistatthesensoryneuronspecificreceptor(SNSR)
AlternativeNames:Bovineadrenalmedullarypeptide-22P,BAM22(1-22)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentendogenousagonistpeptideforthenewlyidentifiedsensoryneuronspecificreceptor(SNSR);isolatedfrombovineadrenalmedulla.EC50valuesare13and16nMforhumanSNSR3andSNSR4respectively.Alsopotentopioidagonist(IC50=1.3nMinguineapigileumpreparation).Producesopioid-andnon-opioidreceptormediatedantinociceptiveeffectsinvivo.

TechnicalData

M.Wt2839.24
FormulaC130H184N38O31S2
SequenceYGGFMRRVGRPEWWMDYQKRYG
StorageDesiccateat-20°C
CASNumber76622-26-9
PubChemID16132339
InChIKeyQYDAFJUKVGVEKO-PKOVDKIBSA-N
Smiles[H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2839.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.35mL1.76mL3.52mL
5mM0.07mL0.35mL0.7mL
10mM0.04mL0.18mL0.35mL
50mM0.01mL0.04mL0.07mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet