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Description:OpioidreceptoragoNIST.Alsoagonistatthesensoryneuronspecificreceptor(SNSR)
AlternativeNames:Bovineadrenalmedullarypeptide-22P,BAM22(1-22)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Potentendogenousagonistpeptideforthenewlyidentifiedsensoryneuronspecificreceptor(SNSR);isolatedfrombovineadrenalmedulla.EC50valuesare13and16nMforhumanSNSR3andSNSR4respectively.Alsopotentopioidagonist(IC50=1.3nMinguineapigileumpreparation).Producesopioid-andnon-opioidreceptormediatedantinociceptiveeffectsinvivo.
TechnicalData
M.Wt | 2839.24 |
Formula | C130H184N38O31S2 |
Sequence | YGGFMRRVGRPEWWMDYQKRYG |
Storage | Desiccateat-20°C |
CASNumber | 76622-26-9 |
PubChemID | 16132339 |
InChIKey | QYDAFJUKVGVEKO-PKOVDKIBSA-N |
Smiles | [H]N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC1=CC=C(O)C=C1)C(=O)NCC(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight2839.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 0.35mL | 1.76mL | 3.52mL |
5mM | 0.07mL | 0.35mL | 0.7mL |
10mM | 0.04mL | 0.18mL | 0.35mL |
50mM | 0.01mL | 0.04mL | 0.07mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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