Tocris多肽 Tocris配体,Tocris/BAY-u 3405/2732/50/50 mg,受体,生物分子,生化试剂,,Tocris Bioscience蚂蚁淘商城

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Tocris/BAY-u 3405/2732/50/50 mg

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Tocris

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2732/50

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4000-520-616

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Description:DualTP/DP₂(CRTH2)receptorantagoNIST

AlternativeNames:Ramatroban

ChemicalName:(3R)-3-[[(4-Fluorophenyl)sulfonyl]amino]-1,2,3,4-tetrahydro-9H-carbazole-9-propanoicacid

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentdualantagonistofTP/DP₂(CRTH2)prostanoidreceptors(K_ivaluesare4.3,4.5and>10000nMforhDP₂,hTPandhDP₁receptorsrespectively).SuppressesPGD₂-inducedmigrationofhumaneosinophils(IC₅₀=170nM).

TechnicalData

M.Wt	416.47
Formula	C₂₁H₂₁FN₂O₄S
Storage	Desiccateat-20°C
Purity	≥99%(HPLC)
CASNumber	116649-85-5
PubChemID	123879
InChIKey	LDXDSHIEDAPSSA-OAHLLOKOSA-N
Smiles	FC(C=C4)=CC=C4S(N[C@@H](C3)CCC2=C3C1=CC=CC=C1N2CCC(O)=O)(=O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	41.65	100
	ethanol	41.65	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight416.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.4mL	12.01mL	24.01mL
5mM	0.48mL	2.4mL	4.8mL
10mM	0.24mL	1.2mL	2.4mL
50mM	0.05mL	0.24mL	0.48mL

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