BiologicalActivity
HighaffinityI2ligand(Ki=9.8nM).PutativeI2agonist;potentiatesmorphineantinociception.Producesipsiversiverotationalbehaviorinratswithafull6-OHDAlesionofthenigrostriataltract.
TechnicalData
| M.Wt | 222.67 |
| Formula | C11H10N2O.HCl |
| Storage | DesiccateatRT |
| CASNumber | 89196-95-2 |
| PubChemID | 45073465 |
| InChIKey | RFNFFVDVGWOSNZ-UHFFFAOYSA-N |
| Smiles | Cl.C1CN=C(N1)C1=CC2=CC=CC=C2O1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto100mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight222.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.49mL | 22.45mL | 44.91mL |
| 5mM | 0.9mL | 4.49mL | 8.98mL |
| 10mM | 0.45mL | 2.25mL | 4.49mL |
| 50mM | 0.09mL | 0.45mL | 0.9mL |
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