BiologicalActivity
HighaffinityandselectiveEP4antagonist(Ki=3nM).Exhibits>2500-foldselectivityforEP4overEP2andEP3.Alsoselectiveoverarangeofotherprostanoidreceptors,ionchannels,transportersandenzymes.InhibitsPGE2-inducedvasodilationofmiddlecerebralandmeningealarteriesinvitro,andcarotidbloodflowinvivo.Orallybioavailable.
TechnicalData
| M.Wt | 529 |
| Formula | C26H24N2O6S.HCl |
| Storage | DesiccateatRT |
| Purity | ≥98%(HPLC) |
| PubChemID | 121513858 |
| InChIKey | ZSHYZCXOFPPBMH-UHFFFAOYSA-N |
| Smiles | CC(OC(C(NS(C4=CC=CC=C4C)(=O)=O)=O)=C3)=C3COC(C=C2)=CC=C2C1=NC=C(OC)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 49.25 | 100 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight529.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.89mL | 9.45mL | 18.9mL |
| 5mM | 0.38mL | 1.89mL | 3.78mL |
| 10mM | 0.19mL | 0.95mL | 1.89mL |
| 50mM | 0.04mL | 0.19mL | 0.38mL |
MolarityCalculator
ReconstitutionCalculator
DilutionCalculator
ProductDatasheets
© 2005- 苏州蚂蚁淘生物科技有限公司 版权所有。
苏ICP备17049038号-11
苏公网安备 32059002001627号
声明：本网站部分产品受外界条件影响（包含但不限于进口国出口国政策限制等因素），无法提供销售服务，下单后，会由客服人员联系厂家确认后另行通知。部分危险品无法清关，请勿下单
我要提问
您的问题将推送给已购用户，TA们将会为你解答。