BiologicalActivity
Selective,highaffinity5-HT6antagonist(Ki=20nM).Reversestheamnesiceffectsofscopolamine(Cat.No.1414)andenhancesmemoryconsolidationinaratmodel.
TechnicalData
| M.Wt | 294.39 |
| Formula | C19H22N2O |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 17375-63-2 |
| PubChemID | 6918515 |
| InChIKey | VSGPGYWZVPDDSK-UHFFFAOYSA-N |
| Smiles | CN(CCC2=C(C3=CC=CC=C3)NC1=CC=C(OC)C=C12)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 29.44 | 100 | |
| ethanol | 14.72 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight294.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.4mL | 16.98mL | 33.97mL |
| 5mM | 0.68mL | 3.4mL | 6.79mL |
| 10mM | 0.34mL | 1.7mL | 3.4mL |
| 50mM | 0.07mL | 0.34mL | 0.68mL |
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