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Description:Highaffinity5-HT6antagoNIST
ChemicalName:5-Methoxy-N,N-dimethyl-2-phenyl-1H-indole-3-ethanamine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Selective,highaffinity5-HT6antagonist(Ki=20nM).Reversestheamnesiceffectsofscopolamine(Cat.No.1414)andenhancesmemoryconsolidationinaratmodel.
TechnicalData
M.Wt | 294.39 |
Formula | C19H22N2O |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 17375-63-2 |
PubChemID | 6918515 |
InChIKey | VSGPGYWZVPDDSK-UHFFFAOYSA-N |
Smiles | CN(CCC2=C(C3=CC=CC=C3)NC1=CC=C(OC)C=C12)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 29.44 | 100 | |
ethanol | 14.72 | 50 |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight294.39.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.4mL | 16.98mL | 33.97mL |
5mM | 0.68mL | 3.4mL | 6.79mL |
10mM | 0.34mL | 1.7mL | 3.4mL |
50mM | 0.07mL | 0.34mL | 0.68mL |
MolarityCalculator
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Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
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DilutionCalculator
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ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet
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