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Tocris/rac BHFF/3313/10/10 mg

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Tocris

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3313/10

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4000-520-616

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Description:Potent,selectiveGABA_Bpositiveallostericmodulator

ChemicalName:5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveGABA_BreceptorpositiveallostericmodulatorthatincreasesthepotencyandefficacyofGABA(>15-foldand>149%respectively).Exhibitsanxiolyticactivityinvivoandisorallyactive.

CompoundLibraries

racBHFFisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	330.34
Formula	C₁₇H₂₁F₃O₃
Storage	Storeat+4°C
Purity	≥98%(HPLC)
CASNumber	123557-91-5
PubChemID	4332683
InChIKey	RVNOANDLZIIFHB-UHFFFAOYSA-N
Smiles	CC(C)(C)C1=C2C(C(O)(C(F)(F)F)C(O2)=O)=CC(C(C)(C)C)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	DMSO	33.03	100
	ethanol	33.03	100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight330.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	3.03mL	15.14mL	30.27mL
5mM	0.61mL	3.03mL	6.05mL
10mM	0.3mL	1.51mL	3.03mL
50mM	0.06mL	0.3mL	0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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