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Tocris/Bicalutamide/3389/50/50 mg
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Tocris/Bicalutamide/3389/50/50 mg
品牌 / 
Tocris
货号 / 
3389/50
美元价:
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数    量:
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4000-520-616
Description:Non-steroidalandrogenreceptorantagoNIST
AlternativeNames:Casodex,ICI176,334
ChemicalName:N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Orallyactivenon-steroidalandrogenreceptorantagonist(IC50=190nM).DisplaysperipheralselectivityanddoesnoteffectserumlevelsofLHandtestosterone.Exhibitspotentanticanceractivityinvivo.

LicensingInformation

SoldforresearchpurposesonlyunderagreementfromAstraZeneca

CompoundLibraries

BicalutamideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt430.37
FormulaC18H14F4N2O4S
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber90357-06-5
PubChemID2375
InChIKeyLKJPYSCBVHEWIU-UHFFFAOYSA-N
SmilesO=C(C(O)(C)CS(C2=CC=C(F)C=C2)(=O)=O)NC1=CC(C(F)(F)F)=C(C#N)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.04100
ethanol4.310

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight430.37.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.32mL11.62mL23.24mL
5mM0.46mL2.32mL4.65mL
10mM0.23mL1.16mL2.32mL
50mM0.05mL0.23mL0.46mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet