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Tocris/<em>nor</em>-Binaltorphimine dihydrochloride/0347/10/10 mg

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Tocris/nor-Binaltorphimine dihydrochloride/0347/10/10 mg

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Tocris

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0347/10

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4000-520-616

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Description:StandardκselectiveantagoNIST

AlternativeNames:nor-BNI,Norbinaltorphimine

ChemicalName:17,17'-(Dicyclopropylmethyl)-6,6',7,7'-6,6'-imino-7,7'-binorphinan-3,4',14,14'-tetroldihydrochloride

Purity:≥98%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Aselectiveκ-opioidreceptorantagonist.

LicensingInformation

SoldwiththepermissionoftheUniversityofMinnesota

CompoundLibraries

nor-BinaltorphiminedihydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	734.72
Formula	C₄₀H₄₃N₃O₆.2HCl
Storage	StoreatRT
Purity	≥98%(HPLC)
CASNumber	113158-34-2
PubChemID	11957626
InChIKey	JOJPJLHRMGPDPV-LZQROVCBSA-N
Smiles	OC1=CC=C2C([C@]34CCN5CC6CC6)=C1O[C@H]4C%11=C(C7=C(N%11)[C@H]%10[C@@]8(CC%13)[C@@]([C@H](N%13CC%12CC%12)CC9=C8C(O%10)=C(O)C=C9)(O)C7)C[C@@]3(O)[C@H]5C2.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
	phosphatebufferedsaline	36.74	50mMwithgentlewarming
	DMSO	18.37	25
	water	18.37	25mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight734.72.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	1.36mL	6.81mL	13.61mL
5mM	0.27mL	1.36mL	2.72mL
10mM	0.14mL	0.68mL	1.36mL
50mM	0.03mL	0.14mL	0.27mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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