![Tocris/Lys-[Des-Arg<sup>9</sup>]Bradykinin/3225/1/1 mg](images/201712/1512521756115821138.jpg)
BiologicalActivity
EndogenouspotentandhighlyselectivebradykininB1receptoragonist(Kivaluesare0.12and>30000nMathumanB1andB2receptorsrespectively).Hypotensiveagentthatreducesperipheralvascularresistanceinvivo.16-foldmorepotentthan[Des-Arg9]-Bradykinin(CatNo.3005).
TechnicalData
| M.Wt | 1032.21 |
| Formula | C50H73N13O11 |
| Sequence | KRPPGFSPF |
| Storage | Desiccateat-20°C |
| CASNumber | 71800-36-7 |
| PubChemID | 122227 |
| InChIKey | AILVBOHFGXNHCC-TZPCGENMSA-N |
| Smiles | [H]N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto1mg/mlinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight1032.21.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.97mL | 4.84mL | 9.69mL |
| 5mM | 0.19mL | 0.97mL | 1.94mL |
| 10mM | 0.1mL | 0.48mL | 0.97mL |
| 50mM | 0.02mL | 0.1mL | 0.19mL |
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