BiologicalActivity
Selective,brainpenetrantGABABreceptorantagonist(IC50=34μMasmeasuredinratcorticalmembranes).Hashigheraffinityforpostsynapticversuspresynapticreceptors.
LicensingInformation
SoldwiththepermissionofNovartisPharmaAG
TechnicalData
| M.Wt | 225.22 |
| Formula | C8H20NO4P |
| Storage | StoreatRT |
| CASNumber | 123690-79-9 |
| PubChemID | 107699 |
| InChIKey | QIIVUOWTHWIXFO-UHFFFAOYSA-N |
| Smiles | NCCCP(C(OCC)OCC)(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
| Solubility | Solubleto100mMinwater |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight225.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.44mL | 22.2mL | 44.4mL |
| 5mM | 0.89mL | 4.44mL | 8.88mL |
| 10mM | 0.44mL | 2.22mL | 4.44mL |
| 50mM | 0.09mL | 0.44mL | 0.89mL |
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