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Tocris/CGP 54626 hydrochloride/1088/50/50 mg
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Tocris/CGP 54626 hydrochloride/1088/50/50 mg
品牌 / 
Tocris
货号 / 
1088/50
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数    量:
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4000-520-616
Description:Potent,selectiveGABABantagoNIST
ChemicalName:[S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl)phosphinicacid
Purity:≥96%
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Apotent,selectiveGABABreceptorantagonist(IC50=4nM).

LicensingInformation

SoldwiththepermissionofNovartisPharmaAG

CompoundLibraries

CGP54626hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt444.76
FormulaC18H28Cl2NO3P.HCl
StorageStoreatRT
Purity≥96%
CASNumber149184-21-4
PubChemID197583
InChIKeyZQCFHOVIXCJPLE-LINSIKMZSA-N
SmilesOP(CC1CCCCC1)(C[C@@H](O)CN[C@@H](C)C2=CC(Cl)=C(Cl)C=C2)=O.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.2450
ethanol4.4510mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight444.76.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.25mL11.24mL22.48mL
5mM0.45mL2.25mL4.5mL
10mM0.22mL1.12mL2.25mL
50mM0.04mL0.22mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet