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Description:Potent,selectiveGABABantagoNIST
ChemicalName:[S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl)phosphinicacid
Purity:≥96%
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences
BiologicalActivity
Apotent,selectiveGABABreceptorantagonist(IC50=4nM).
LicensingInformation
SoldwiththepermissionofNovartisPharmaAG
CompoundLibraries
CGP54626hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
TechnicalData
M.Wt | 444.76 |
Formula | C18H28Cl2NO3P.HCl |
Storage | StoreatRT |
Purity | ≥96% |
CASNumber | 149184-21-4 |
PubChemID | 197583 |
InChIKey | ZQCFHOVIXCJPLE-LINSIKMZSA-N |
Smiles | OP(CC1CCCCC1)(C[C@@H](O)CN[C@@H](C)C2=CC(Cl)=C(Cl)C=C2)=O.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
SolubilityData
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 22.24 | 50 | |
ethanol | 4.45 | 10mMwithgentlewarming |
PreparingStockSolutions
Thefollowingdataisbasedontheproductmolecularweight444.76.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.25mL | 11.24mL | 22.48mL |
5mM | 0.45mL | 2.25mL | 4.5mL |
10mM | 0.22mL | 1.12mL | 2.25mL |
50mM | 0.04mL | 0.22mL | 0.45mL |
MolarityCalculator
MolarityCalculator
Calculatethemass,volume,orconcentrationrequiredforasolution.
ReconstitutionCalculator
ReconstitutionCalculator
DilutionCalculator
DilutionCalculator
Calculatethedilutionrequiredtoprepareastocksolution.
ProductDatasheets
CertificateofAnalysis/ProductDatasheet
SafetyDatasheet


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